Retina

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Retina December 2023

Choroidal Vascularity Index Fluctuations in Epiretinal Membranes in Vitreoretinal Surgery: Comparison Between Idiopathic and Diabetic Ones

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Rossella D'Aloisio; Maria Ludovica Ruggeri; Annamaria Porreca; Marta Di Nicola; Agbéanda Aharrh-Gnama; Alberto Quarta; Matteo Gironi; Lisa Toto; Rodolfo Mastropasqua
TAGS: cardiovascular imaging, cortical blindness, diabetes mellitus, epiretinal membrane, retinal surgery, vitreoretinal surgery, surgical procedures, operative, vitrectomy, eye
Trans. Vis. Sci. Tech.. 2023; 12(12):9. https://doi.org/10.1167/tvst.12.12.9

Visual Psychophysics and Physiological Optics December 2023

The Influence of Phosphene Synchrony in Driving Object Binding in a Simulation of Artificial Vision

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Noya Meital-Kfir; John S. Pezaris
TAGS: accommodation phosphene, artificial vision, reading (activity)
Invest. Ophthalmol. Vis. Sci.. 2023; 64(15):5. https://doi.org/10.1167/iovs.64.15.5

Glaucoma December 2023

Reducing Ophthalmic Health Disparities Through Transfer Learning: A Novel Application to Overcome Data Inequality

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TingFang Lee; Gadi Wollstein; Chisom T. Madu; Andrew Wronka; Lei Zheng; Ronald Zambrano; Joel S. Schuman; Jiyuan Hu
TAGS: eye, health disparity, imbalance, learning, transfer technique
Trans. Vis. Sci. Tech.. 2023; 12(12):2. https://doi.org/10.1167/tvst.12.12.2

Retina December 2023

Correlation Between Vitreous Level of Angiogenic Growth Factors and Oxygen Saturation in Retinal Vessels in Diabetic Retinopathy

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Hana Morin; Jan Havlík; Oldřich Chrapek; Michal Hrevuš; Pavel Němec; Leoš Rejmont; Jan Tesař; Marta Kalousova; Tomaš Zima; Martin Šín
TAGS: angiogenesis, diabetic retinopathy, growth factor, oxygen saturation measurement, retinal vessels, vitreous body, oximetry, vascular endothelial growth factor a, diabetes mellitus
Invest. Ophthalmol. Vis. Sci.. 2023; 64(15):4. https://doi.org/10.1167/iovs.64.15.4

Retinal Cell Biology December 2023

Diabetes Modulates Iodothyronine Deiodinase 2 Expression in the Mouse Retina: A Role for Thyroid Hormone in the Pathogenesis of Diabetic Retinopathy

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Reena Bapputty; Hima Sapa; Miyagi Masaru; Rose A. Gubitosi-Klug
TAGS: diabetes mellitus, diabetes mellitus, type 2, diabetic retinopathy, glucose, iodide peroxidase, mice, pathogenesis, retina, thyroid hormones, sequence analysis, rna
Invest. Ophthalmol. Vis. Sci.. 2023; 64(15):3. https://doi.org/10.1167/iovs.64.15.3

Includes: Supplemental Content

Anatomy and Pathology/Oncology December 2023

Vitreous Humor Proteomic Profile in Patients With Vitreoretinal Lymphoma

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Hiroyuki Komatsu; Yoshihiko Usui; Kinya Tsubota; Risa Fujii; Takefumi Yamaguchi; Kazuichi Maruyama; Ryo Wakita; Masaki Asakage; Kazuki Hamada; Naoyuki Yamakawa; Naoya Nezu; Koji Ueda; Hiroshi Goto
TAGS: primary vitreoretinal lymphoma, proteins, vitreous body, ocular sarcoidosis
Invest. Ophthalmol. Vis. Sci.. 2023; 64(15):2. https://doi.org/10.1167/iovs.64.15.2

Includes: Supplemental Content

Retinal Cell Biology December 2023

Diabetic Müller-Glial-Cell-Specific Il6ra Knockout Mice Exhibit Accelerated Retinal Functional Decline and Thinning of the Inner Nuclear Layer

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Joshua Glass; Rebekah L. Robinson; Grace Greenway; Garrett Jones; Shruti Sharma
TAGS: diabetes mellitus, mice, diabetic retinopathy, mice, knockout, electroretinography
Invest. Ophthalmol. Vis. Sci.. 2023; 64(15):1. https://doi.org/10.1167/iovs.64.15.1

Includes: Supplemental Content

Telemedicine November 2023

Development of LuxIA, a Cloud-Based AI Diabetic Retinopathy Screening Tool Using a Single Color Fundus Image

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Joseph P. M. Blair; Jose Natan Rodriguez; Romina M. Lasagni Vitar; Marc A. Stadelmann; Rodrigo Abreu-González; Juan Donate; Carlos Ciller; Stefanos Apostolopoulos; Carlos Bermudez; Sandro De Zanet
TAGS: color, datasets, diabetic retinopathy screening, screening, training, diabetes mellitus, specialism
Trans. Vis. Sci. Tech.. 2023; 12(11):38. https://doi.org/10.1167/tvst.12.11.38

Includes: Supplemental Content

Clinical and Epidemiologic Research November 2023

Association of Age-Related Macular Degeneration with a Blood Biomarker of Lipopolysaccharide, a Gut Bacterial Proinflammatory Toxin

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Petra P. Larsen; Catherine Féart; Jean-Paul Pais de Barros; Benedicte M. J. Merle; Laure Gayraud; Marie-Noëlle Delyfer; Jean-François Korobelnik; Cécile Delcourt
TAGS: age-related macular degeneration, biological markers, cd95 antigens, fatty-acid synthase, fetal alcohol syndrome, lipopolysaccharides, plasma, toxins, cohort studies, endotoxins
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):47. https://doi.org/10.1167/iovs.64.14.47

Includes: Supplemental Content

Cornea November 2023

Correlation Between Corneal Whorl-Like Nerve and Retinal Neurodegenerative Changes and Their Association With Microvessel Perfusion in Diabetes

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Dongyu Li; Xin Jin; Chao Wang; Nan Zhang; Di Jin; Hong Zhang
TAGS: cornea, diabetes mellitus, diabetes mellitus, type 2, microvessels, neurons, perfusion, retina
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):44. https://doi.org/10.1167/iovs.64.14.44

Retina November 2023

Investigating the Spatiotemporal Summation of Perimetric Stimuli in Dry Age-Related Macular Degeneration

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Aoife M. L. Hunter; Roger S. Anderson; Tony Redmond; David F. Garway-Heath; Pádraig J. Mulholland
TAGS: age-related macular degeneration, spatial summation, summation, temporal summation, visual fields, perimetry, significance
Trans. Vis. Sci. Tech.. 2023; 12(11):37. https://doi.org/10.1167/tvst.12.11.37

Retina November 2023

An Evaluation of the Repeatability of Visual Function Following Surgical Repair of Macula-Off Rhegmatogenous Retinal Detachment

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Michael J. Huvard; Jennifer L. Patnaik; David M. Kleinman; Mary Preston; David N. Zacks; Andrew J. Kocab; Jana van de Goor; Brandie D. Wagner; Steve Cho; Anne M. Lynch; Naresh Mandava
TAGS: eye, macula lutea, retinal detachment, rhegmatogenous retinal detachment, surgical procedures, operative, vision
Trans. Vis. Sci. Tech.. 2023; 12(11):35. https://doi.org/10.1167/tvst.12.11.35

Includes: Supplemental Content

Research Opportunities November 2023

Report From the 2022 Mary Tyler Moore Vision Initiative Diabetic Retinal Disease Clinical Endpoints Workshop

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S. Robert Levine; Martin G. Myers; Ryan Barunas; Dolly S. Chang; Sanjoy Dutta; Ted Maddess; Jeffrey M. Liebmann; Steve Sherman; Melvina Eydelman; Jennifer K. Sun; Wiley Chambers; Kerstin Wickström; Ulrich F. O. Luhmann; Martin Pallinat; Adam Glassman; Lloyd Paul Aiello; Dorene S. Markel; Thomas W. Gardner
TAGS: diabetes mellitus, retinal diseases, surrogate endpoints, vision
Trans. Vis. Sci. Tech.. 2023; 12(11):33. https://doi.org/10.1167/tvst.12.11.33

Includes: Supplemental Content

Retina November 2023

GSK840 Alleviates Retinal Neuronal Injury by Inhibiting RIPK3/MLKL-Mediated RGC Necroptosis After Ischemia/Reperfusion

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Yanlin Feng; Chenyang Hu; Kaixuan Cui; Matthew Fan; Wu Xiang; Dan Ye; Yuxun Shi; Huiwen Ye; Xue Bai; Yantao Wei; Yue Xu; Jingjing Huang
TAGS: ischemia, necroptosis, reperfusion therapy, wounds and injuries, physiologic reperfusion, retina
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):42. https://doi.org/10.1167/iovs.64.14.42

Includes: Supplemental Content

Retinal Cell Biology November 2023

Essential Role of XBP1 in Maintaining Photoreceptor Synaptic Integrity in Early Diabetic Retinopathy

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Todd McLaughlin; Grant Wang; Andy Medina; Jacob Perkins; Rhudwan Nihlawi; Don Seyfried; Zihua Hu; Joshua J. Wang; Sarah X. Zhang
TAGS: diabetes mellitus, diabetic retinopathy, mice, personal integrity, photoreceptors, electroretinography, retina, synapses
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):40. https://doi.org/10.1167/iovs.64.14.40

Includes: Supplemental Content

Glaucoma November 2023

Nicotinamide Prevents Retinal Vascular Dropout in a Rat Model of Ocular Hypertension and Supports Ocular Blood Supply in Glaucoma Patients

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Simon T. Gustavsson; Tim J. Enz; James R. Tribble; Mattias Nilsson; Anna Lindqvist; Christina Lindén; Anna Hagström; Carola Rutigliani; Emma Lardner; Gustav Stålhammar; Pete A. Williams; Gauti Jóhannesson
TAGS: glaucoma, niacinamide, ocular hypertension, retinal vasculature, vasculature, vascular flow, eye, optic disk
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):34. https://doi.org/10.1167/iovs.64.14.34

Includes: Supplemental Content

Retina November 2023

A Microfluidic Platform for the Time-Resolved Interrogation of Polarized Retinal Pigment Epithelial Cells

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Eric C. Spivey; Jinggang Yin; Edward Chaum; John P. Wikswo
TAGS: retinal pigment cell, vascular endothelial growth factor a, fluid flow, bodily secretions, hypoxia
Trans. Vis. Sci. Tech.. 2023; 12(11):28. https://doi.org/10.1167/tvst.12.11.28

Includes: Supplemental Content

Retina November 2023

Deep Learning–Facilitated Study of the Rate of Change in Photoreceptor Outer Segment Metrics in RPGR -Related X-Linked Retinitis Pigmentosa

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Yi-Zhong Wang; Katherine Juroch; Yineng Chen; Gui-Shuang Ying; David G. Birch
TAGS: deep learning, photoreceptors, retinitis pigmentosa, volume, x-linked inheritance, eye, baseline value, follow-up, disease progression
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):31. https://doi.org/10.1167/iovs.64.14.31

Retina November 2023

The Impact of Diabetic Retinopathy on the Choriocapillaris in Neovascular AMD

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Pasquale Viggiano; Alexandra Miere; Enrico Borrelli; Giacomo Boscia; Maria Oliva Grassi; Eric H. Souied; Giovanni Alessio; Francesco Boscia
TAGS: chief complaint, diabetic retinopathy, exudative age-related macular degeneration, eye, macular neovascularization, fluid flow
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):32. https://doi.org/10.1167/iovs.64.14.32

Physiology and Pharmacology November 2023

O-GlcNAcylation Inhibition Upregulates Connexin43 Expression in the Endothelium to Protect the Tight Junction Barrier in Diabetic Retinopathy

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Guodong Liu; Le Feng; Xiaoqiang Liu; Peng Gao; Fang Wang
TAGS: connexin 43, tight junctions, glucose, diabetic retinopathy
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):30. https://doi.org/10.1167/iovs.64.14.30

Includes: Supplemental Content

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Choroidal Vascularity Index Fluctuations in Epiretinal Membranes in Vitreoretinal Surgery: Comparison Between Idiopathic and Diabetic Ones

The Influence of Phosphene Synchrony in Driving Object Binding in a Simulation of Artificial Vision

Reducing Ophthalmic Health Disparities Through Transfer Learning: A Novel Application to Overcome Data Inequality

Correlation Between Vitreous Level of Angiogenic Growth Factors and Oxygen Saturation in Retinal Vessels in Diabetic Retinopathy

Diabetes Modulates Iodothyronine Deiodinase 2 Expression in the Mouse Retina: A Role for Thyroid Hormone in the Pathogenesis of Diabetic Retinopathy

Vitreous Humor Proteomic Profile in Patients With Vitreoretinal Lymphoma

Diabetic Müller-Glial-Cell-Specific Il6ra Knockout Mice Exhibit Accelerated Retinal Functional Decline and Thinning of the Inner Nuclear Layer

Development of LuxIA, a Cloud-Based AI Diabetic Retinopathy Screening Tool Using a Single Color Fundus Image

Association of Age-Related Macular Degeneration with a Blood Biomarker of Lipopolysaccharide, a Gut Bacterial Proinflammatory Toxin

Correlation Between Corneal Whorl-Like Nerve and Retinal Neurodegenerative Changes and Their Association With Microvessel Perfusion in Diabetes

Investigating the Spatiotemporal Summation of Perimetric Stimuli in Dry Age-Related Macular Degeneration

An Evaluation of the Repeatability of Visual Function Following Surgical Repair of Macula-Off Rhegmatogenous Retinal Detachment

Report From the 2022 Mary Tyler Moore Vision Initiative Diabetic Retinal Disease Clinical Endpoints Workshop

GSK840 Alleviates Retinal Neuronal Injury by Inhibiting RIPK3/MLKL-Mediated RGC Necroptosis After Ischemia/Reperfusion

Essential Role of XBP1 in Maintaining Photoreceptor Synaptic Integrity in Early Diabetic Retinopathy

Nicotinamide Prevents Retinal Vascular Dropout in a Rat Model of Ocular Hypertension and Supports Ocular Blood Supply in Glaucoma Patients

A Microfluidic Platform for the Time-Resolved Interrogation of Polarized Retinal Pigment Epithelial Cells

Deep Learning–Facilitated Study of the Rate of Change in Photoreceptor Outer Segment Metrics in RPGR -Related X-Linked Retinitis Pigmentosa

The Impact of Diabetic Retinopathy on the Choriocapillaris in Neovascular AMD

O-GlcNAcylation Inhibition Upregulates Connexin43 Expression in the Endothelium to Protect the Tight Junction Barrier in Diabetic Retinopathy

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