Retina

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Retina July 2017

A Pharmacodynamic Analysis of Choroidal Neovascularization in a Porcine Model Using Three Targeted Drugs

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Jeffrey Tran; Caroline Craven; Kathy Wabner; Jenn Schmit; Brock Matter; Uday Kompella; Hans E. Grossniklaus; Timothy W. Olsen
TAGS: choroidal neovascularization, surgical procedures, operative, family suidae, pazopanib
Invest. Ophthalmol. Vis. Sci.. 2017; 58(9):3732-3740. doi: 10.1167/iovs.16-21230

Retinal Cell Biology July 2017

Molecular Pathway to Protection From Age-Dependent Photoreceptor Degeneration in Mef2 Deficiency

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Saumya Nagar; Dorit Trudler; Scott R. McKercher; Juan Piña-Crespo; Nobuki Nakanishi; Shu-Ichi Okamoto; Stuart A. Lipton
TAGS: photoreceptors, mice, retina, myocyte-specific enhancer-binding factor 2, tissue degeneration
Invest. Ophthalmol. Vis. Sci.. 2017; 58(9):3741-3749. doi: 10.1167/iovs.17-21767

Includes: Supplemental Content

Retina July 2017

Posterior Staphylomas in Pathologic Myopia Imaged by Widefield Optical Coherence Tomography

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Kosei Shinohara; Noriaki Shimada; Muka Moriyama; Takeshi Yoshida; Jost B. Jonas; Nagahisa Yoshimura; Kyoko Ohno-Matsui
TAGS: eye, sclera, staphyloma, myopic macular degeneration, optical coherence tomography, 3d mri
Invest. Ophthalmol. Vis. Sci.. 2017; 58(9):3750-3758. doi: 10.1167/iovs.17-22319

Glaucoma July 2017

Variation in the Three-Dimensional Histomorphometry of the Normal Human Optic Nerve Head With Age and Race: Lamina Cribrosa and Peripapillary Scleral Thickness and Position

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Christopher A. Girkin; Massimo A. Fazio; Hongli Yang; Juan Reynaud; Claude F. Burgoyne; Brandon Smith; Lan Wang; J. Crawford Downs
TAGS: optic disk, racial group, reconstructive surgical procedures, body tissue, eye, sclera, cribriform plate, donors
Invest. Ophthalmol. Vis. Sci.. 2017; 58(9):3759-3769. doi: 10.1167/iovs.17-21842

Includes: Multimedia, Supplemental Content

Retina July 2017

Reliability and Repeatability of Cone Density Measurements in Patients With Stargardt Disease and RPGR -Associated Retinopathy

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Preena Tanna; Melissa Kasilian; Rupert Strauss; James Tee; Angelos Kalitzeos; Sergey Tarima; Alexis Visotcky; Alfredo Dubra; Joseph Carroll; Michel Michaelides
TAGS: retinal cone, retinal diseases, mosaicism, reliability, stargardt's disease
Invest. Ophthalmol. Vis. Sci.. 2017; 58(9):3608-3615. doi: 10.1167/iovs.17-21904

Retina July 2017

Indocyanine Green Angiography and Optical Coherence Tomography Angiography of Choroidal Neovascularization in Age-Related Macular Degeneration

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Chiara M. Eandi; Antonio Ciardella; Mariacristina Parravano; Filippo Missiroli; Camilla Alovisi; Chiara Veronese; Maria C. Morara; Massimo Grossi; Gianni Virgili; Federico Ricci
TAGS: angiogram, age-related macular degeneration, indocyanine green angiography, age-related macular degeneration, exudative, optical coherence tomography, choroidal neovascularization
Invest. Ophthalmol. Vis. Sci.. 2017; 58(9):3690-3696. doi: 10.1167/iovs.17-21941

Retina July 2017

Functional Reading Independence (FRI) Index: A New Patient-Reported Outcome Measure for Patients With Geographic Atrophy

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Miriam Kimel; Nancy Kline Leidy; Elizabeth Tschosik; Chantal Dolan; Eric H. Souied; Rohit Varma; Neil M. Bressler
TAGS: validity of results, atrophy, interviews, psychometrics, reading (activity), reliability, content validity, patient self-report
Invest. Ophthalmol. Vis. Sci.. 2017; 57(14):6298-6304. doi: 10.1167/iovs.16-20361

Includes: Supplemental Content

Retinal Cell Biology July 2017

TNFα-Induced Disruption of the Blood–Retinal Barrier In Vitro Is Regulated by Intracellular 3′,5′-Cyclic Adenosine Monophosphate Levels

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Anne-Eva van der Wijk; Ilse M. C. Vogels; Cornelis J. F. van Noorden; Ingeborg Klaassen; Reinier O. Schlingemann
TAGS: adenosine monophosphate, blood-retinal barrier, permeability, cyclic amp
Invest. Ophthalmol. Vis. Sci.. 2017; 58(9):3496-3505. doi: 10.1167/iovs.16-21091

Includes: Supplemental Content

Research Opportunities July 2017

Report From the NEI/FDA Endpoints Workshop on Age-Related Macular Degeneration and Inherited Retinal Diseases

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Karl Csaky; Frederick Ferris, III; Emily Y. Chew; Prashant Nair; Janet K. Cheetham; Jacque L. Duncan
TAGS: retinal diseases, united states food and drug administration, eye, age-related macular degeneration, surrogate endpoints
Invest. Ophthalmol. Vis. Sci.. 2017; 58(9):3456-3463. doi: 10.1167/iovs.17-22339

Clinical and Epidemiologic Research July 2017

Correlations Between Macular, Skin, and Serum Carotenoids

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Christopher D. Conrady; James P. Bell; Brian M. Besch; Aruna Gorusupudi; Kelliann Farnsworth; Igor Ermakov; Mohsen Sharifzadeh; Maia Ermakova; Werner Gellermann; Paul S. Bernstein
TAGS: carotenoids, skin, macular pigment
Invest. Ophthalmol. Vis. Sci.. 2017; 58(9):3616-3627. doi: 10.1167/iovs.17-21818

Low Vision July 2017

Blur Adaptation to Central Retinal Disease

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Fuensanta A. Vera-Diaz; Russell L. Woods; Eli Peli
TAGS: perception, retinal diseases, vision
Invest. Ophthalmol. Vis. Sci.. 2017; 58(9):3646-3655. doi: 10.1167/iovs.16-20849

Retina July 2017

Glucocorticoid-Induced Leucine Zipper Protects the Retina From Light-Induced Retinal Degeneration by Inducing Bcl-xL in Rats

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Ruiping Gu; Wenyi Tang; Boya Lei; Xinyi Ding; Cheng Jiang; Gezhi Xu
TAGS: apoptosis, glucocorticoids, electroretinography, leucine zippers, retinal degeneration, wounds and injuries, rats, retina, bcl-xl protein, protein overexpression, exposure to light, opportunity for error
Invest. Ophthalmol. Vis. Sci.. 2017; 58(9):3656-3668. doi: 10.1167/iovs.17-22116

Includes: Supplemental Content

Retina July 2017

OCT Angiography and Ellipsoid Zone Mapping of Macular Telangiectasia Type 2 From the AVATAR Study

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Anne P. Runkle; Peter K. Kaiser; Sunil K. Srivastava; Andrew P. Schachat; Jamie L. Reese; Justis P. Ehlers
TAGS: angiogram, telangiectasis, visual acuity, blood capillaries, diagnostic imaging, eye
Invest. Ophthalmol. Vis. Sci.. 2017; 58(9):3683-3689. doi: 10.1167/iovs.16-20976

Review July 2017

Algorithms for the Automated Analysis of Age-Related Macular Degeneration Biomarkers on Optical Coherence Tomography: A Systematic Review

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Maximilian W.M. Wintergerst; Thomas Schultz; Johannes Birtel; Alexander K. Schuster; Norbert Pfeiffer; Steffen Schmitz-Valckenberg; Frank G. Holz; Robert P. Finger
TAGS: drusen, atrophy, biological markers, age-related macular degeneration, review, systematic, optical coherence tomography, retinal pigment epithelial detachment
Trans. Vis. Sci. Tech.. 2017; 6(4):10. doi: 10.1167/tvst.6.4.10

Includes: Supplemental Content

Articles July 2017

Associations between Optic Nerve Head–Related Anatomical Parameters and Refractive Error over the Full Range of Glaucoma Severity

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Neda Baniasadi; Mengyu Wang; Hui Wang; Mufeed Mahd; Tobias Elze
TAGS: glaucoma, optic disk, refractive errors
Trans. Vis. Sci. Tech.. 2017; 6(4):9. doi: 10.1167/tvst.6.4.9

Includes: Supplemental Content

Articles July 2017

Validity, Usefulness and Cost of RET eval System for Diabetic Retinopathy Screening

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Humoud Al-Otaibi; Mohammed D. Al-Otaibi; Rajiv Khandekar; Ches Souru; Abdulelah A. Al-Abdullah; Hassan Al-Dhibi; Donald U. Stone; Igor Kozak
TAGS: diabetes mellitus, validity of results, eye, retina, screening, fundus photography, diabetic retinopathy screening
Trans. Vis. Sci. Tech.. 2017; 6(3):3. doi: 10.1167/tvst.6.3.3

Special Issue July 2017

Incidence and Factors Influencing Retinal Displacement in Eyes Treated for Rhegmatogenous Retinal Detachment With Vitrectomy and Gas or Silicone Oil

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Roberto dell'Omo; Andrea Scupola; Davide Viggiano; Maria Grazia Sammarco; Serena De Turris; Mario R. Romano; Gabriela Grimaldi; Ermanno dell'Omo; Ciro Costagliola
TAGS: macula lutea, silicone oils, surgical procedures, operative, vitrectomy, incidence, eye, retina, rhegmatogenous retinal detachment, macula densa, radiation recall dermatitis
Invest. Ophthalmol. Vis. Sci.. 2017; 58(6):BIO191-BIO199. doi: 10.1167/iovs.17-21466

Clinical and Epidemiologic Research July 2017

Optical Coherence Tomography Features Preceding the Onset of Advanced Age-Related Macular Degeneration

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Daniela Ferrara; Rachel E. Silver; Ricardo N. Louzada; Eduardo A. Novais; Giliann K. Collins; Johanna M. Seddon
TAGS: eye, age-related macular degeneration, optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2017; 58(9):3519-3529. doi: 10.1167/iovs.17-21696

Includes: Supplemental Content

Retina July 2017

Inter-Relationship of Arterial Supply to Human Retina, Choroid, and Optic Nerve Head Using Micro Perfusion and Labeling

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Paula K. Yu; Ian L. McAllister; William H. Morgan; Stephen J. Cringle; Dao-Yi Yu
TAGS: blood coagulation factor vii, catheterization, optic disk, perfusion, choroid, eye, microbiology procedure, retina, probes, fluorescent, blood supply, arterial, donors
Invest. Ophthalmol. Vis. Sci.. 2017; 58(9):3565-3574. doi: 10.1167/iovs.17-22191

Retina July 2017

A Quantitative and Qualitative Exploration of Photoaversion in Achromatopsia

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Jonathan Aboshiha; Neruban Kumaran; Angelos Kalitzeos; Chris Hogg; Gary Rubin; Michel Michaelides
TAGS: eyelid, lighting, photophobia, signs and symptoms, visual acuity, eye, achromatopsia, surveys, luminance
Invest. Ophthalmol. Vis. Sci.. 2017; 58(9):3537-3546. doi: 10.1167/iovs.17-21935

Includes: Supplemental Content

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A Pharmacodynamic Analysis of Choroidal Neovascularization in a Porcine Model Using Three Targeted Drugs

Molecular Pathway to Protection From Age-Dependent Photoreceptor Degeneration in Mef2 Deficiency

Posterior Staphylomas in Pathologic Myopia Imaged by Widefield Optical Coherence Tomography

Variation in the Three-Dimensional Histomorphometry of the Normal Human Optic Nerve Head With Age and Race: Lamina Cribrosa and Peripapillary Scleral Thickness and Position

Reliability and Repeatability of Cone Density Measurements in Patients With Stargardt Disease and RPGR -Associated Retinopathy

Indocyanine Green Angiography and Optical Coherence Tomography Angiography of Choroidal Neovascularization in Age-Related Macular Degeneration

Functional Reading Independence (FRI) Index: A New Patient-Reported Outcome Measure for Patients With Geographic Atrophy

TNFα-Induced Disruption of the Blood–Retinal Barrier In Vitro Is Regulated by Intracellular 3′,5′-Cyclic Adenosine Monophosphate Levels

Report From the NEI/FDA Endpoints Workshop on Age-Related Macular Degeneration and Inherited Retinal Diseases

Correlations Between Macular, Skin, and Serum Carotenoids

Blur Adaptation to Central Retinal Disease

Glucocorticoid-Induced Leucine Zipper Protects the Retina From Light-Induced Retinal Degeneration by Inducing Bcl-xL in Rats

OCT Angiography and Ellipsoid Zone Mapping of Macular Telangiectasia Type 2 From the AVATAR Study

Algorithms for the Automated Analysis of Age-Related Macular Degeneration Biomarkers on Optical Coherence Tomography: A Systematic Review

Associations between Optic Nerve Head–Related Anatomical Parameters and Refractive Error over the Full Range of Glaucoma Severity

Validity, Usefulness and Cost of RET eval System for Diabetic Retinopathy Screening

Incidence and Factors Influencing Retinal Displacement in Eyes Treated for Rhegmatogenous Retinal Detachment With Vitrectomy and Gas or Silicone Oil

Optical Coherence Tomography Features Preceding the Onset of Advanced Age-Related Macular Degeneration

Inter-Relationship of Arterial Supply to Human Retina, Choroid, and Optic Nerve Head Using Micro Perfusion and Labeling

A Quantitative and Qualitative Exploration of Photoaversion in Achromatopsia

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