Cornea

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Cornea & External Disease December 2024

Quantifying the Corneal Nerve Whorl Pattern

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Maryse Lapierre-Landry; Eric Y. Lu; Matthew T. McPheeters; Made Airanthi K. Widjaja-Adhi; David L. Wilson; Rony R. Sayegh; Patricia R. Taylor; Marcin Golczak; Michael W. Jenkins
TAGS: cornea, datasets, neurons, mice, diabetes mellitus
Trans. Vis. Sci. Tech.. 2024; 13(12):11. https://doi.org/10.1167/tvst.13.12.11

Includes: Supplemental Content

Cornea December 2024

Atg5-Mediated Lipophagy Induces Ferroptosis in Corneal Epithelial Cells in Dry Eye Disease

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Xin Zuo; Hao Zeng; Xue Yang; Dalian He; Bowen Wang; Jin Yuan
TAGS: corneal epithelial cells, dry eye syndromes, ferroptosis, loeys-dietz syndrome, proteins, stress, western blotting, autophagy, lipid peroxidation, lysosomes
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):12. https://doi.org/10.1167/iovs.65.14.12

Includes: Supplemental Content

Cornea December 2024

A Sex-Dependent Cannabinoid CB1 Receptor Role in Circadian Tearing of the Mouse

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Natalia Murataeva; Kyle Yust; Sam Mattox; Wenwen Du; Alex Straiker
TAGS: cannabinoids, mice, proteins
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):10. https://doi.org/10.1167/iovs.65.14.10

Cornea November 2024

cRGD-Conjugated Bilirubin Nanoparticles Alleviate Dry Eye Disease Via Activating the PINK1-Mediated Mitophagy

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Yang Huang; Lijun Wang; Haiying Jin
TAGS: bilirubin, cornea, dry eye syndromes, mice, mitophagy, nadph oxidase 4, nanoparticles, ocular surfaces, pink1 gene, nitric oxide synthase
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):55. https://doi.org/10.1167/iovs.65.13.55

Includes: Supplemental Content

Clinical Trials November 2024

A Comparative and Prospective Study of Corneal Consumption and Corneal Biomechanics After SMILE and FS-LASIK Performed on the Contralateral Eyes With High Myopic Astigmatism

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Xiangtao Hou; Pei Chen; Na Yu; Yiqi Luo; Han Wei; Jing Zhuang; Keming Yu
TAGS: astigmatism, biomechanics, cardiac ct, cornea, eye, keratomileusis, laser in situ, laser surgery, prospective studies, surgical procedures, operative
Trans. Vis. Sci. Tech.. 2024; 13(11):29. https://doi.org/10.1167/tvst.13.11.29

Cornea & External Disease November 2024

Investigating the Tolerance of Corneal Endothelial Cells to Surgical Fluid Pressure Using Intact Porcine Eyes

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Alex J. McMullen; Zaynab A. Dantsoho; Scott Chamness; John Brunelle; Jaime Martiz; Yousuf M. Khalifa; Mark R. Buckley
TAGS: cornea, eye, scirrhous adenocarcinoma, suidae, surgical procedures, operative, endothelial cells
Trans. Vis. Sci. Tech.. 2024; 13(11):27. https://doi.org/10.1167/tvst.13.11.27

Includes: Supplemental Content

Cornea & External Disease November 2024

Efficacy of Terpinen-4-ol Combined With Eyelid Deep Cleaning for the Treatment of Demodex Blepharitis: A Randomized, Open-Label Trial

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Hao-Yu Wang; Dan Shen; Meng-Ying Qi; Chen Qiao; Lan Ke; Mingwu Wang; Qing-Yan Zeng
TAGS: blepharitis, eyelid, mites, ocular surfaces, eyelid margin, follow-up
Trans. Vis. Sci. Tech.. 2024; 13(11):22. https://doi.org/10.1167/tvst.13.11.22

Cornea & External Disease November 2024

Exploring New Links Among Keratoconus, Hormonal Factors, and Medications: Insights From a Case–Control Study Utilizing the All of Us Database

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Carol Beatty; Amy Estes; Hongyan Xu; Yutao Liu
TAGS: estrogen, keratoconus, pharmaceutical preparations, risk factors, obesity, medical history, dry eye syndromes
Trans. Vis. Sci. Tech.. 2024; 13(11):18. https://doi.org/10.1167/tvst.13.11.18

Cornea November 2024

Deletion of Fgfr2 in Ductal Basal Epithelium With Tamoxifen Induces Obstructive Meibomian Gland Dysfunction

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Xiaowei Yang; Xingwu Zhong; Haotian Lin; Andrew J.W. Huang; Lixing W. Reneker
TAGS: atrophy, epithelium, fgfr2 gene, meibomian gland dysfunction, mice, tamoxifen
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):36. https://doi.org/10.1167/iovs.65.13.36

Includes: Supplemental Content

Cornea November 2024

Restoration of Corneal Stiffness in Rabbits Following Withdrawal of Travoprost

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XiaoBo Zheng; Chong Wang; YiWen Fan; YuXin Hong; Han Bao; ErChi Zhang; Yi Jin; Peng Yang; LingQiao Li; JunJie Wang; ShiHao Chen; Ahmed Elsheikh; FangJun Bao
TAGS: cornea, oryctolagus cuniculus, travoprost, cardiac ct, multiple wake test, eye
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):35. https://doi.org/10.1167/iovs.65.13.35

Cornea November 2024

De-Differentiation of Corneal Epithelial Cells Into Functional Limbal Epithelial Stem Cells After the Ablation of Innate Stem Cells

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Yijian Li; Lingling Ge; Bangqi Ren; Xue Zhang; Zhiyuan Yin; Hongling Liu; Yuli Yang; Yong Liu; Haiwei Xu
TAGS: ablation, chronic exertional compartment syndrome, cornea, stem cells, epithelium
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):32. https://doi.org/10.1167/iovs.65.13.32

Includes: Supplemental Content

Refractive Intervention November 2024

Characterization of Disrupted Tissue Interface Thickness for Keratorefractive Lenticule Extraction Procedure With ELITA Femtosecond Laser

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Hajime Minoguchi; Athiyya Umar; Hong Fu
TAGS: body tissue, eye, femtosecond pulsed lasers, lasers, cornea, surgical flaps
Trans. Vis. Sci. Tech.. 2024; 13(11):3. https://doi.org/10.1167/tvst.13.11.3

Immunology and Microbiology November 2024

γδ T17 Cells Regulate the Acute Antiviral Response of NK Cells in HSV-1–Infected Corneas

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Rachel R. Rodenberg; Domenico Spadafora; Steffani Fitzpatrick; Grant Daly; Robert Lausch; Robert A. Barrington
TAGS: antiviral agents, cornea, human herpesvirus 1, interleukin-17, mice, natural killer cells, infections
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):16. https://doi.org/10.1167/iovs.65.13.16

Includes: Supplemental Content

Cornea November 2024

Determining the Relationship Between Corneal Stiffening and Tissue Dehydration After Corneal Cross-Linking

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Raymundo Rodríguez-López; Joshua N. Webb; Metecan Erdi; Peter Kofinas; Walfre Franco; Hongyuan Zhang; James Bradley Randleman; Giuliano Scarcelli
TAGS: body tissue, cornea, corneal collagen cross-linking, cross-linking, dehydration, dehydration of tissue specimen
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):14. https://doi.org/10.1167/iovs.65.13.14

Includes: Supplemental Content

Cornea November 2024

PINK1/Parkin-Mediated Mitophagy Ameliorates Mitochondrial Dysfunction in Lacrimal Gland Acinar Cells During Aging

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Han Zhao; Yue Zhang; Yujie Ren; Wanpeng Wang
TAGS: aging, lacrimal gland, mice, mitochondria, mitophagy, park2 gene, pink1 gene, rapamycin, acinar cells, pathophysiology
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):12. https://doi.org/10.1167/iovs.65.13.12

Includes: Supplemental Content

Cornea November 2024

Mechanisms Regulating Mitochondrial Transfer in Human Corneal Epithelial Cells

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Sonali Pal-Ghosh; Beverly A. Karpinski; Himani Datta-Majumdar; Soneha Datta; Shelly Dimri; Jordan Hally; Hugo Wehmeyer; Mary Ann Stepp
TAGS: mitochondria, mitochondrial donation, phagocytosis, corneal epithelial cells, neurons, cell adhesion
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):10. https://doi.org/10.1167/iovs.65.13.10

Includes: Supplemental Content

Cornea November 2024

Silencing METTL3 Increases HSP70 Expression and Alleviates Fibrosis in Keratocytes

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Yapeng Jing; Jun Li; Peng Hao; Shulei Xing; Xuan Li
TAGS: acute erythroblastic leukemia, cornea, fibrosis, heat-shock proteins 70, keratocytes, alkalies, burns
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):9. https://doi.org/10.1167/iovs.65.13.9

Includes: Supplemental Content

Cornea & External Disease October 2024

The Increase in Corneal Stiffness After Accelerated Corneal Cross-Linking in Progressive Keratoconus Using Different Methods of Epithelial Debridement

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Robert Herber; Dierk Wittig; Felix Lochmann; Lutz E. Pillunat; Frederik Raiskup
TAGS: cornea, corneal collagen cross-linking, epithelium, keratoconus, debridement
Trans. Vis. Sci. Tech.. 2024; 13(10):38. https://doi.org/10.1167/tvst.13.10.38

Cornea October 2024

PAX6–WNK2 Axis Governs Corneal Epithelial Homeostasis

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Liqiong Zhu; Chaoqun Chen; Siqi Wu; Huizhen Guo; Lingyu Li; Li Wang; Dongmei Liu; Yu Zhan; Xinyue Du; Jiafeng Liu; Jieying Tan; Ying Huang; Kunlun Mo; Xihong Lan; Hong Ouyang; Jin Yuan; Xiangjun Chen; Jianping Ji
TAGS: cornea, homeostasis, pax6 transcription factor, scirrhous adenocarcinoma, epithelium, chronic exertional compartment syndrome, genes
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):40. https://doi.org/10.1167/iovs.65.12.40

Includes: Supplemental Content

Cornea October 2024

ALKBH5 Regulates Corneal Neovascularization by Mediating FOXM1 M6A Demethylation

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Wei Wang; Hua Li; Yiyong Qian; Min Li; Manli Deng; Dexi Bi; Jun Zou
TAGS: acute erythroblastic leukemia, alkalies, burns, choroidal neovascularization, cornea, corneal neovascularization, demethylation, forkhead box protein m1, neovascularization, pathologic, mice
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):34. https://doi.org/10.1167/iovs.65.12.34

Includes: Supplemental Content

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Quantifying the Corneal Nerve Whorl Pattern

Atg5-Mediated Lipophagy Induces Ferroptosis in Corneal Epithelial Cells in Dry Eye Disease

A Sex-Dependent Cannabinoid CB1 Receptor Role in Circadian Tearing of the Mouse

cRGD-Conjugated Bilirubin Nanoparticles Alleviate Dry Eye Disease Via Activating the PINK1-Mediated Mitophagy

A Comparative and Prospective Study of Corneal Consumption and Corneal Biomechanics After SMILE and FS-LASIK Performed on the Contralateral Eyes With High Myopic Astigmatism

Investigating the Tolerance of Corneal Endothelial Cells to Surgical Fluid Pressure Using Intact Porcine Eyes

Efficacy of Terpinen-4-ol Combined With Eyelid Deep Cleaning for the Treatment of Demodex Blepharitis: A Randomized, Open-Label Trial

Exploring New Links Among Keratoconus, Hormonal Factors, and Medications: Insights From a Case–Control Study Utilizing the All of Us Database

Deletion of Fgfr2 in Ductal Basal Epithelium With Tamoxifen Induces Obstructive Meibomian Gland Dysfunction

Restoration of Corneal Stiffness in Rabbits Following Withdrawal of Travoprost

De-Differentiation of Corneal Epithelial Cells Into Functional Limbal Epithelial Stem Cells After the Ablation of Innate Stem Cells

Characterization of Disrupted Tissue Interface Thickness for Keratorefractive Lenticule Extraction Procedure With ELITA Femtosecond Laser

γδ T17 Cells Regulate the Acute Antiviral Response of NK Cells in HSV-1–Infected Corneas

Determining the Relationship Between Corneal Stiffening and Tissue Dehydration After Corneal Cross-Linking

PINK1/Parkin-Mediated Mitophagy Ameliorates Mitochondrial Dysfunction in Lacrimal Gland Acinar Cells During Aging

Mechanisms Regulating Mitochondrial Transfer in Human Corneal Epithelial Cells

Silencing METTL3 Increases HSP70 Expression and Alleviates Fibrosis in Keratocytes

The Increase in Corneal Stiffness After Accelerated Corneal Cross-Linking in Progressive Keratoconus Using Different Methods of Epithelial Debridement

PAX6–WNK2 Axis Governs Corneal Epithelial Homeostasis

ALKBH5 Regulates Corneal Neovascularization by Mediating FOXM1 M6A Demethylation

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