Eye Anatomy and Disorders

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Articles May 2022

Automated Assessment of Photoreceptor Visibility in Adaptive Optics Split-Detection Images Using Edge Detection

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Min Chen; Yu You Jiang; James C. Gee; David H. Brainard; Jessica I. W. Morgan
TAGS: optics, photoreceptors
Trans. Vis. Sci. Tech.. 2022; 11(5):25. doi: https://doi.org/10.1167/tvst.11.5.25

Includes: Supplemental Content

Genetics May 2022

Different Phenotypes Represent Advancing Stages of ABCA4 -Associated Retinopathy: A Longitudinal Study of 212 Chinese Families From a Tertiary Center

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Yingwei Wang; Wenmin Sun; Jing Zhou; Xueqing Li; Yi Jiang; Shiqiang Li; Xiaoyun Jia; Xueshan Xiao; Jiamin Ouyang; Yueye Wang; Lin Zhou; Yuxi Long; Mengchu Liu; Yongyu Li; Zhen Yi; Panfeng Wang; Qingjiong Zhang
TAGS: abca4 gene, chinese (other dialects), chinese people, longitudinal studies, phenotype, retinal diseases, family
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):28. doi: https://doi.org/10.1167/iovs.63.5.28

Includes: Supplemental Content

Genetics May 2022

Identification of a Complex Allele in IMPG2 as a Cause of Adult-Onset Vitelliform Macular Dystrophy

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Irene Vázquez-Domínguez; Catherina H. Z. Li; Zeinab Fadaie; Lonneke Haer-Wigman; Frans P. M. Cremers; Alejandro Garanto; Carel B. Hoyng; Susanne Roosing
TAGS: adult, alleles, persistent postconcussive syndrome, postpolypectomy coagulation syndrome, vitelliform dystrophy, exons, rna splicing, genes
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):27. doi: https://doi.org/10.1167/iovs.63.5.27

Includes: Supplemental Content

Glaucoma May 2022

Ocular and Hemodynamic Factors Contributing to the Central Visual Function in Glaucoma Patients With Myopia

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Kyung Euy Hong; Seong Ah Kim; Da-Young Shin; Chan Kee Park; Hae-Young Lopilly Park
TAGS: glaucoma, hemodynamics, myopia, vascular flow, vision, scotoma, central
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):26. doi: https://doi.org/10.1167/iovs.63.5.26

Glaucoma May 2022

Microstructural Deformations Within the Depth of the Lamina Cribrosa in Response to Acute In Vivo Intraocular Pressure Modulation

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Yoav Glidai; Katie A. Lucy; Joel S. Schuman; Palaiologos Alexopoulos; Bo Wang; Mengfei Wu; Mengling Liu; Jonathan P. Vande Geest; Hirut G. Kollech; TingFang Lee; Hiroshi Ishikawa; Gadi Wollstein
TAGS: cribriform plate, eye, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):25. doi: https://doi.org/10.1167/iovs.63.5.25

Includes: Supplemental Content

Anatomy and Pathology/Oncology May 2022

Scleral Cross-Linking in Form-Deprivation Myopic Guinea Pig Eyes Leads to Glaucomatous Changes

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Lei Guo; Rui Hua; Xinxin Zhang; Ting Yu Yan; Yang Tong; Xin Zhao; Shi Chao Chen; Moying Wang; Neil M. Bressler; Jun Kong
TAGS: corneal collagen cross-linking, cross-linking, eye, glaucoma, guinea, sclera, myopia
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):24. doi: https://doi.org/10.1167/iovs.63.5.24

Articles May 2022

Electrophysiological Assessment in Birdshot Chorioretinopathy: Flicker Electroretinograms Recorded With a Handheld Device

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Anna M. Waldie; Angharad E. Hobby; Isabelle Chow; Elisa E. Cornish; Mathura Indusegaran; Aleksandra Pekacka; Phuc Nguyen; Clare Fraser; Alison M. Binns; Miles R. Stanford; Christopher J. Hammond; Peter J. McCluskey; John R. Grigg; Omar A. Mahroo
TAGS: electroretinography, mobile devices, photopsia, vitiliginous chorioretinitis, electrophysiology
Trans. Vis. Sci. Tech.. 2022; 11(5):23. doi: https://doi.org/10.1167/tvst.11.5.23

Articles May 2022

Sex and Age-Related Differences in Complement Factors Among Patients With Intermediate Age-Related Macular Degeneration

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A. Itzam Marin; Felix Poppelaars; Brandie D. Wagner; Alan G. Palestine; Jennifer L. Patnaik; V. Michael Holers; Ashley A. Frazer-Abel; Marc T. Mathias; Niranjan Manoharan; Cheryl N. Fonteh; Naresh Mandava; Anne M. Lynch; for the University of Colorado Retina Research Group
TAGS: age-related macular degeneration, complement system proteins
Trans. Vis. Sci. Tech.. 2022; 11(5):22. doi: https://doi.org/10.1167/tvst.11.5.22

Includes: Supplemental Content

Articles May 2022

Dynamic Pressure Measurements During Vitrectomy in a Model of the Eye

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Irene Nepita; Alessandro Stocchino; Andrea Dodero; Maila Castellano; Mariantonia Ferrara; Mario R. Romano; Rodolfo Repetto
TAGS: eye, infusion procedures, intraocular pressure, vitrectomy, vitreous body, pulmonary aspiration, surgical procedures, operative, aspirations (psychology)
Trans. Vis. Sci. Tech.. 2022; 11(5):21. doi: https://doi.org/10.1167/tvst.11.5.21

Articles May 2022

Contrast-to-Noise Ratios to Evaluate the Detection of Glaucomatous Progression in the Superior and Inferior Hemiretina

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Juleke E.A. Majoor; Koenraad A. Vermeer; Hans G. Lemij
TAGS: glaucoma, noise, retinal nerve fiber layer, eye
Trans. Vis. Sci. Tech.. 2022; 11(5):20. doi: https://doi.org/10.1167/tvst.11.5.20

Articles May 2022

Comparison of Cone Mosaic Metrics From Images Acquired With the SPECTRALIS High Magnification Module and Adaptive Optics Scanning Light Ophthalmoscopy

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Niamh Wynne; Heather Heitkotter; Erica N. Woertz; Robert F. Cooper; Joseph Carroll
TAGS: diagnostic imaging, magnification, mosaicism, ophthalmoscopy, optics, retinal cone, photoreceptors, image quality
Trans. Vis. Sci. Tech.. 2022; 11(5):19. doi: https://doi.org/10.1167/tvst.11.5.19

Includes: Multimedia, Supplemental Content

Letters to the Editor May 2022

Author Response: Smokers’ Choroidal Changes

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Xin Wei; Rupesh Agrawal
TAGS: smokers
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):22. doi: https://doi.org/10.1167/iovs.63.5.22

Letters to the Editor May 2022

Smokers’ Choroidal Changes

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Alessio Marino; Ciro Sannino; Nicola Rosa
TAGS: smokers
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):21. doi: https://doi.org/10.1167/iovs.63.5.21

Visual Neuroscience May 2022

The Association Between Acquired Color Deficiency and PET Imaging of Neurodegeneration in Mild Cognitive Impairment and Alzheimer Disease

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Kallene Summer Moreira Vidal; Diego Decleva; Mirella Telles Salgueiro Barboni; Balàzs Vince Nagy; Paulo Augusto Hidalgo de Menezes; Avinash Aher; Artur Martins Coutinho; Paula Squarzoni; Daniele de Paula Faria; Fabio Luis de Souza Duran; Carlos Alberto Buchpiguel; Jan Kremers; Geraldo Busatto Filho; Dora Fix Ventura
TAGS: alzheimer's disease, brain, color, color vision, electroretinography, heart failure, minimal cognitive impairment, nerve degeneration, positron-emission tomography
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):20. doi: https://doi.org/10.1167/iovs.63.5.20

Includes: Supplemental Content

Genetics May 2022

Autosomal Dominant Retinitis Pigmentosa–Associated TOPORS Protein Truncating Variants Are Exclusively Located in the Region of Amino Acid Residues 807 to 867

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Junwen Wang; Yingwei Wang; Yi Jiang; Xueqing Li; Xueshan Xiao; Shiqiang Li; Xiaoyun Jia; Wenmin Sun; Panfeng Wang; Qingjiong Zhang
TAGS: amino acids, proteins, retinitis pigmentosa, datasets, cohort studies
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):19. doi: https://doi.org/10.1167/iovs.63.5.19

Includes: Supplemental Content

Retina May 2022

Single-Cell Protein and Transcriptional Characterization of Epiretinal Membranes From Patients With Proliferative Vitreoretinopathy

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Yannik Laich; Julian Wolf; Rozina Ida Hajdu; Anja Schlecht; Felicitas Bucher; Laurenz Pauleikhoff; Martin Busch; Gottfried Martin; Henrik Faatz; Saskia Killmer; Bertram Bengsch; Andreas Stahl; Albrecht Lommatzsch; Günther Schlunck; Hansjürgen Agostini; Stefaniya Boneva; Clemens Lange
TAGS: epiretinal membrane, proteins, tissue membrane, transcription, genetic, vitreoretinopathy, proliferative, sequence analysis, rna, diagnostic imaging, body tissue
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):17. doi: https://doi.org/10.1167/iovs.63.5.17

Includes: Supplemental Content

Cornea May 2022

Comprehensive Analysis Identified the Circadian Clock and Global Circadian Gene Expression in Human Corneal Endothelial Cells

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Hiroko Nakai; Yoshiki Tsuchiya; Nobuya Koike; Taiki Asano; Morio Ueno; Yasuhiro Umemura; Yuh Sasawaki; Ryutaro Ono; Junji Hamuro; Chie Sotozono; Kazuhiro Yagita
TAGS: circadian clocks, cornea, endothelial cells, gene expression, chronic exertional compartment syndrome, genes, rhythm, bioluminescence
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):16. doi: https://doi.org/10.1167/iovs.63.5.16

Includes: Multimedia, Supplemental Content

Articles May 2022

Characterization and Validation of In Vitro and In Vivo Models to Investigate TNF-α-Induced Inflammation in Retinal Diseases

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Carina M. Weigelt; Nina Zippel; Holger Fuchs; Anna-Kaisa Rimpelä; Tanja Schönberger; Birgit Stierstorfer; Remko A. Bakker; Norbert H. Redemann
TAGS: golimumab, inflammation, mice, retinal diseases, tumor necrosis factors
Trans. Vis. Sci. Tech.. 2022; 11(5):18. doi: https://doi.org/10.1167/tvst.11.5.18

Includes: Supplemental Content

Articles May 2022

Early Diagnosis and Quantitative Analysis of Stages in Retinopathy of Prematurity Based on Deep Convolutional Neural Networks

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Peng Li; Jia Liu
TAGS: convolutional neural networks, datasets, early diagnosis, retinopathy of prematurity, training, infant, premature, ophthalmologists
Trans. Vis. Sci. Tech.. 2022; 11(5):17. doi: https://doi.org/10.1167/tvst.11.5.17

Articles May 2022

Characterizing Visual Fields in RPGR Related Retinitis Pigmentosa Using Octopus Static-Automated Perimetry

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Thomas M. W. Buckley; Amandeep Singh Josan; Laura J. Taylor; Jasleen K. Jolly; Jasmina Cehajic-Kapetanovic; Robert E. MacLaren
TAGS: octopus, perimetry, retinitis pigmentosa, visual fields
Trans. Vis. Sci. Tech.. 2022; 11(5):15. doi: https://doi.org/10.1167/tvst.11.5.15

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Automated Assessment of Photoreceptor Visibility in Adaptive Optics Split-Detection Images Using Edge Detection

Different Phenotypes Represent Advancing Stages of ABCA4 -Associated Retinopathy: A Longitudinal Study of 212 Chinese Families From a Tertiary Center

Identification of a Complex Allele in IMPG2 as a Cause of Adult-Onset Vitelliform Macular Dystrophy

Ocular and Hemodynamic Factors Contributing to the Central Visual Function in Glaucoma Patients With Myopia

Microstructural Deformations Within the Depth of the Lamina Cribrosa in Response to Acute In Vivo Intraocular Pressure Modulation

Scleral Cross-Linking in Form-Deprivation Myopic Guinea Pig Eyes Leads to Glaucomatous Changes

Electrophysiological Assessment in Birdshot Chorioretinopathy: Flicker Electroretinograms Recorded With a Handheld Device

Sex and Age-Related Differences in Complement Factors Among Patients With Intermediate Age-Related Macular Degeneration

Dynamic Pressure Measurements During Vitrectomy in a Model of the Eye

Contrast-to-Noise Ratios to Evaluate the Detection of Glaucomatous Progression in the Superior and Inferior Hemiretina

Comparison of Cone Mosaic Metrics From Images Acquired With the SPECTRALIS High Magnification Module and Adaptive Optics Scanning Light Ophthalmoscopy

Author Response: Smokers’ Choroidal Changes

Smokers’ Choroidal Changes

The Association Between Acquired Color Deficiency and PET Imaging of Neurodegeneration in Mild Cognitive Impairment and Alzheimer Disease

Autosomal Dominant Retinitis Pigmentosa–Associated TOPORS Protein Truncating Variants Are Exclusively Located in the Region of Amino Acid Residues 807 to 867

Single-Cell Protein and Transcriptional Characterization of Epiretinal Membranes From Patients With Proliferative Vitreoretinopathy

Comprehensive Analysis Identified the Circadian Clock and Global Circadian Gene Expression in Human Corneal Endothelial Cells

Characterization and Validation of In Vitro and In Vivo Models to Investigate TNF-α-Induced Inflammation in Retinal Diseases

Early Diagnosis and Quantitative Analysis of Stages in Retinopathy of Prematurity Based on Deep Convolutional Neural Networks

Characterizing Visual Fields in RPGR Related Retinitis Pigmentosa Using Octopus Static-Automated Perimetry

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