Eye Anatomy and Disorders

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Anatomy and Pathology/Oncology June 2023

In Vitro Testing of the Virus-Like Drug Conjugate Belzupacap Sarotalocan (AU-011) on Uveal Melanoma Suggests BAP1-Related Immunostimulatory Capacity

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Sen Ma; Ruben V. Huis In't Veld; Alexander Houy; Marc-Henri Stern; Cadmus Rich; Ferry A. Ossendorp; Martine J. Jager
TAGS: bap1 gene, cell lines, drug conjugates, hsp90 heat-shock proteins, intraocular melanoma, viruses, cytotoxicity, cell death
Invest. Ophthalmol. Vis. Sci.. 2023; 64(7):10. doi: https://doi.org/10.1167/iovs.64.7.10

Includes: Supplemental Content

Genetics June 2023

Associations of VEGF Polymorphisms With Retinopathy of Prematurity

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Xiao Chun Ling; Eugene Yu-Chuan Kang; Kuan-Jen Chen; Nan-Kai Wang; Laura Liu; Yen-Po Chen; Yih-Shiou Hwang; Chi-Chun Lai; Shun-Fa Yang; Wei-Chi Wu
TAGS: polymorphism, retinopathy of prematurity, vascular endothelial growth factor a, infant
Invest. Ophthalmol. Vis. Sci.. 2023; 64(7):11. doi: https://doi.org/10.1167/iovs.64.7.11

Includes: Supplemental Content

Retina June 2023

Sortilin Inhibition Protects Neurons From Degeneration in the Diabetic Retina

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Thomas Stax Jakobsen; Jakob Appel Østergaard; Mads Kjolby; Elisa Lund Birch; Toke Bek; Anders Nykjaer; Thomas J. Corydon; Anne Louise Askou
TAGS: diabetes mellitus, mice, retina, nerve degeneration, tissue degeneration
Invest. Ophthalmol. Vis. Sci.. 2023; 64(7):8. doi: https://doi.org/10.1167/iovs.64.7.8

Includes: Supplemental Content

Biochemistry and Molecular Biology June 2023

Selective BD2 Inhibitor Exerts Anti-Fibrotic Effects via BRD4/FoxM1/Plk1 Axis in Orbital Fibroblasts From Patients With Thyroid Eye Disease

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Yanyan Xie; Yuan Pan; Qian Chen; Yuxi Chen; Guanyu Chen; Mei Wang; Peng Zeng; Zhuang Li; Zuoyi Li; Sha Wang; Huasheng Yang; Dan Liang
TAGS: fibrosis, forkhead box protein m1, graves' ophthalmopathy, fibroblasts, proteins
Invest. Ophthalmol. Vis. Sci.. 2023; 64(7):9. doi: https://doi.org/10.1167/iovs.64.7.9

Includes: Supplemental Content

Article June 2023

Zooming in on style: Exploring style perception using details of paintings

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Yuguang Zhao; Jeroen Stumpel; Huib de Ridder; Maarten W. A. Wijntjes
TAGS: color, malus, paintings, perception, triplets
Journal of Vision. 2023; 23(6):2. doi: https://doi.org/10.1167/jov.23.6.2

Includes: Supplemental Content

Clinical and Epidemiologic Research June 2023

Choroidal Circulation in 8- to 30-Year-Old Chinese, Measured by SS-OCT/OCTA: Relations to Age, Axial Length, and Choroidal Thickness

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Yuanyuan Wang; Mengqi Liu; Zhu Xie; Pengqi Wang; Xiang Li; Xinyuan Yao; Jinmin Tian; Yang Han; Xiangqin Chen; Zhiqiang Xu; Xinjie Mao; Xiangtian Zhou; Jia Qu; Hao Wu
TAGS: chinese (other dialects), chinese people, choroidal circulation, cortical blindness, eye, perfusion, myopia
Invest. Ophthalmol. Vis. Sci.. 2023; 64(7):7. doi: https://doi.org/10.1167/iovs.64.7.7

Includes: Supplemental Content

Biochemistry and Molecular Biology June 2023

HSF4 Transcriptionally Activates Autophagy by Regulating ATG9a During Lens Terminal Differentiation

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Jing Zhang; Ning Jiang; Chunxiao Du; Hongzan Guo; Ranqi Meng; Xinyu Hou; Mugen Liu; Yanzhong Hu; Xiukun Cui
TAGS: autophagy, lens (device), lens, crystalline, mice, rapamycin, catabolism, organelles
Invest. Ophthalmol. Vis. Sci.. 2023; 64(7):5. doi: https://doi.org/10.1167/iovs.64.7.5

Includes: Supplemental Content

Glaucoma June 2023

Racial and Ethnic Differences in the Roles of Myopia and Ocular Biometrics as Risk Factors for Primary Open-Angle Glaucoma

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Sarah Zhou; Bruce Burkemper; Anmol A. Pardeshi; Galo Apolo; Grace Richter; Xuejuan Jiang; Mina Torres; Roberta McKean-Cowdin; Rohit Varma; Benjamin Y. Xu
TAGS: biometry, ethnic group, myopia, open-angle glaucoma, risk factors, ethnic differences, glaucoma
Invest. Ophthalmol. Vis. Sci.. 2023; 64(7):4. doi: https://doi.org/10.1167/iovs.64.7.4

Clinical and Epidemiologic Research June 2023

Age-Related Differences in Ocular Features of a Naturalistic Free-Ranging Population of Rhesus Macaques

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Arthur G. Fernandes; Palaiologos Alexopoulos; Armando Burgos-Rodriguez; Melween I. Martinez; Mark Ghassibi; Ilya Leskov; Lauren J. N. Brent; Noah Snyder-Mackler; John Danias; Gadi Wollstein; James P. Higham; Amanda D. Melin
TAGS: macaca mulatta, cataract, retinal drusen, eye, body weight
Invest. Ophthalmol. Vis. Sci.. 2023; 64(7):3. doi: https://doi.org/10.1167/iovs.64.7.3

Retina June 2023

Low-Dose Trans -Resveratrol Ameliorates Diabetes-Induced Retinal Ganglion Cell Degeneration via TyrRS/c-Jun Pathway

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Ke Xiao; Xiao-Hong Ma; Zheng Zhong; Yin Zhao; Xu-Hui Chen; Xu-Fang Sun
TAGS: diabetes mellitus, ganglia, resveratrol, retinal ganglion cells, tissue degeneration, western blotting, nuclear translocation, apoptosis, phosphorylation
Invest. Ophthalmol. Vis. Sci.. 2023; 64(7):2. doi: https://doi.org/10.1167/iovs.64.7.2

Includes: Supplemental Content

Biochemistry and Molecular Biology June 2023

The Mechanosensitive Piezo1 Channel Mediates Mechanochemical Transmission in Myopic Eyes

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Weiqi Zhong; Changjun Lan; Zhiming Gu; Qingqing Tan; Xiaoling Xiang; Hong Zhou; Xuan Liao
TAGS: eye, myopia, retina, caviidae, proteins, dimethyl sulfoxide
Invest. Ophthalmol. Vis. Sci.. 2023; 64(7):1. doi: https://doi.org/10.1167/iovs.64.7.1

Artificial Intelligence June 2023

Metagenome Investigation of Ocular Microbiota of Cataract Patients With and Without Type 2 Diabetes

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Zheng Shao; Xiaona Shan; Lili Jing; Weina Wang; Wenfeng Li; Zhichao Ren; Bi Ning Zhang; Yusen Huang
TAGS: cataract, diabetes mellitus, type 2, microbiome, ocular surfaces, conjunctival sac
Trans. Vis. Sci. Tech.. 2023; 12(6):1. doi: https://doi.org/10.1167/tvst.12.6.1

Includes: Supplemental Content

Glaucoma May 2023

Neuroretinal Rim Response to Transient Intraocular Pressure Challenge Predicts the Extent of Retinal Ganglion Cell Loss in Experimental Glaucoma

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Nimesh B. Patel; Louvenia Carter-Dawson; Laura J. Frishman
TAGS: glaucoma, intraocular pressure, diagnostic imaging, eye, optic disk, retinal ganglion cells, neuroretinal rim
Invest. Ophthalmol. Vis. Sci.. 2023; 64(5):30. doi: https://doi.org/10.1167/iovs.64.5.30

Includes: Supplemental Content

Cornea May 2023

Z nf469 Plays a Critical Role in Regulating Synthesis of ECM: A Zebrafish Model of Brittle Cornea Syndrome

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Jing Bao; Xiaoning Yu; Xiyuan Ping; Xingchao Shentu; Jian Zou
TAGS: cornea, ehlers-danlos syndrome 6b, mutation, zebrafish, regulation, larva
Invest. Ophthalmol. Vis. Sci.. 2023; 64(5):29. doi: https://doi.org/10.1167/iovs.64.5.29

Includes: Supplemental Content

Retina May 2023

Identification of Five Novel Variants in the TSPAN12 Gene in Chinese Families With Familial Exudative Vitreoretinopathy

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You Wang; Qiong Wang; Songshan Li; Xiaoyan Ding
TAGS: chinese (other dialects), chinese people, familial exudative vitreoretinopathies, family, genes, luciferases
Trans. Vis. Sci. Tech.. 2023; 12(5):29. doi: https://doi.org/10.1167/tvst.12.5.29

Review May 2023

Mechanisms of Acquired Resistance to Anti-VEGF Therapy for Neovascular Eye Diseases

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Dhyana Sharma; Ian Zachary; Haiyan Jia
TAGS: anti-vascular endothelial growth factor therapy, eye diseases, neuropilin-1, vascular endothelial growth factor a, glycolysis, endothelium, angiogenesis
Invest. Ophthalmol. Vis. Sci.. 2023; 64(5):28. doi: https://doi.org/10.1167/iovs.64.5.28

Cornea May 2023

Effects of Mirogabalin on Hyperalgesia and Chronic Ocular Pain in Tear-Deficient Dry-Eye Rats

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Kasumi Kikuchi; Yoshiaki Tagawa; Miyuki Murata; Susumu Ishida
TAGS: cornea, dry eye syndromes, hyperalgesia, ocular pain, rats, eye, excision
Invest. Ophthalmol. Vis. Sci.. 2023; 64(5):27. doi: https://doi.org/10.1167/iovs.64.5.27

Cornea May 2023

Norepinephrine as the Intrinsic Contributor to Contact Lens–Induced Pseudomonas aeruginosa Keratitis

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Bi Ning Zhang; Benxiang Qi; Wai Kit Chu; Fangying Song; Suxia Li; Qiaoqiao Dong; Zheng Shao; Bin Zhang; Xianli Du; Xiubin Ma; Vishal Jhanji; Qingjun Zhou
TAGS: adrb2 gene, beta-2 adrenergic receptors, contact lenses, cornea, infections, keratitis, mice, norepinephrine, pseudomonas aeruginosa, epithelium
Invest. Ophthalmol. Vis. Sci.. 2023; 64(5):26. doi: https://doi.org/10.1167/iovs.64.5.26

Includes: Supplemental Content

Glaucoma May 2023

Influence of a Prostaglandin F2α Analogue on Corneal Hysteresis and Expression of Extracellular Matrix Metalloproteinases 3 and 9

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Constance Weber; Alexandra Buerger; Siegfried Priglinger; Karl Mercieca; Raffael Liegl
TAGS: cornea, corneal hysteresis, extracellular matrix, intraocular pressure, metalloproteases, prostaglandins, prostaglandins, synthetic, stromelysin 1, gelatinase b, donors
Trans. Vis. Sci. Tech.. 2023; 12(5):28. doi: https://doi.org/10.1167/tvst.12.5.28

Article May 2023

The role of habitual learning in premotor attention allocation

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Christof Elias Topfstedt; Luca Wollenberg; Thomas Schenk
TAGS: attention, training, learning
Journal of Vision. 2023; 23(5):19. doi: https://doi.org/10.1167/jov.23.5.19

Includes: Supplemental Content

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In Vitro Testing of the Virus-Like Drug Conjugate Belzupacap Sarotalocan (AU-011) on Uveal Melanoma Suggests BAP1-Related Immunostimulatory Capacity

Associations of VEGF Polymorphisms With Retinopathy of Prematurity

Sortilin Inhibition Protects Neurons From Degeneration in the Diabetic Retina

Selective BD2 Inhibitor Exerts Anti-Fibrotic Effects via BRD4/FoxM1/Plk1 Axis in Orbital Fibroblasts From Patients With Thyroid Eye Disease

Zooming in on style: Exploring style perception using details of paintings

Choroidal Circulation in 8- to 30-Year-Old Chinese, Measured by SS-OCT/OCTA: Relations to Age, Axial Length, and Choroidal Thickness

HSF4 Transcriptionally Activates Autophagy by Regulating ATG9a During Lens Terminal Differentiation

Racial and Ethnic Differences in the Roles of Myopia and Ocular Biometrics as Risk Factors for Primary Open-Angle Glaucoma

Age-Related Differences in Ocular Features of a Naturalistic Free-Ranging Population of Rhesus Macaques

Low-Dose Trans -Resveratrol Ameliorates Diabetes-Induced Retinal Ganglion Cell Degeneration via TyrRS/c-Jun Pathway

The Mechanosensitive Piezo1 Channel Mediates Mechanochemical Transmission in Myopic Eyes

Metagenome Investigation of Ocular Microbiota of Cataract Patients With and Without Type 2 Diabetes

Neuroretinal Rim Response to Transient Intraocular Pressure Challenge Predicts the Extent of Retinal Ganglion Cell Loss in Experimental Glaucoma

Z nf469 Plays a Critical Role in Regulating Synthesis of ECM: A Zebrafish Model of Brittle Cornea Syndrome

Identification of Five Novel Variants in the TSPAN12 Gene in Chinese Families With Familial Exudative Vitreoretinopathy

Mechanisms of Acquired Resistance to Anti-VEGF Therapy for Neovascular Eye Diseases

Effects of Mirogabalin on Hyperalgesia and Chronic Ocular Pain in Tear-Deficient Dry-Eye Rats

Norepinephrine as the Intrinsic Contributor to Contact Lens–Induced Pseudomonas aeruginosa Keratitis

Influence of a Prostaglandin F2α Analogue on Corneal Hysteresis and Expression of Extracellular Matrix Metalloproteinases 3 and 9

The role of habitual learning in premotor attention allocation

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