Glaucoma

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Glaucoma July 2024

Protective Effect of Nicotinamide Riboside on Glucocorticoid-Induced Glaucoma: Mitigating Mitochondrial Damage and Extracellular Matrix Deposition

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Nan Zhang; Pengyu Zhang; Xizhi Deng; Min Zhu; Yixin Hu; Dongxiao Ji; Lufan Li; Yang Liu; Wen Zeng; Min Ke
TAGS: extracellular matrix, glaucoma, glucocorticoids, mitochondria, mitochondrial toxicity, niacinamide, trabecular meshwork, pathophysiology, mice
Invest. Ophthalmol. Vis. Sci.. 2024; 65(8):1. https://doi.org/10.1167/iovs.65.8.1

Includes: Supplemental Content

Glaucoma June 2024

A Practical Framework for the Integration of Structural Data Into Perimetric Examinations

PDF

Josephine C. Evans; Giovanni Ometto; David P. Crabb; Giovanni Montesano
TAGS: glaucoma, perimetry
Trans. Vis. Sci. Tech.. 2024; 13(6):19. https://doi.org/10.1167/tvst.13.6.19

Includes: Supplemental Content

Artificial Intelligence June 2024

Predicting Glaucoma Surgical Outcomes Using Neural Networks and Machine Learning on Electronic Health Records

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Samuel Barry; Sophia Y. Wang
TAGS: electronic medical records, glaucoma, machine learning, surgical outcome, surgical procedures, operative, glaucoma surgery, pharmaceutical preparations, intraocular pressure, surgical failure, preoperative care
Trans. Vis. Sci. Tech.. 2024; 13(6):15. https://doi.org/10.1167/tvst.13.6.15

Includes: Supplemental Content

Glaucoma June 2024

Repeatability of a Virtual Reality Headset Perimeter in Glaucoma and Ocular Hypertensive Patients

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Rafaella Nascimento e Silva; Julia A. Kim; Yihao Li; Chen Chen; Anisa F. Chaudhry; Andrew R. Berneshawi; Miao Zhang; Adam Villarreal; Jocelyn Liu; Ann Shue; Dolly S. Chang; Robert T. Chang
TAGS: glaucoma, ocular hypertension, virtual reality, eye
Trans. Vis. Sci. Tech.. 2024; 13(6):14. https://doi.org/10.1167/tvst.13.6.14

Includes: Supplemental Content

Artificial Intelligence June 2024

Visual Field Prognosis From Macula and Circumpapillary Spectral Domain Optical Coherence Tomography

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Davide Scandella; Mathias Gallardo; Serife S. Kucur; Raphael Sznitman; Jan Darius Unterlauft
TAGS: glaucoma, macula lutea, optic disk, spectral domain-optical coherence tomography, visual fields, cohort studies, retinal nerve fiber layer, deep learning
Trans. Vis. Sci. Tech.. 2024; 13(6):10. https://doi.org/10.1167/tvst.13.6.10

Clinical and Epidemiologic Research June 2024

Applicability of Oculomics for Individual Risk Prediction: Repeatability and Robustness of Retinal Fractal Dimension Using DART and AutoMorph

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Justin Engelmann; Diana Moukaddem; Lucas Gago; Niall Strang; Miguel O. Bernabeu
TAGS: datasets, fractals, image quality, radiation therapy, adaptive, eye, grapes (dietary), noise
Invest. Ophthalmol. Vis. Sci.. 2024; 65(6):10. https://doi.org/10.1167/iovs.65.6.10

Includes: Supplemental Content

Physiology and Pharmacology June 2024

The Factors Affecting the Stability of IOP Homeostasis

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Darryl R. Overby; C. Ross Ethier; Changxu Miao; Ruth A. Kelly; Ester Reina-Torres; W. Daniel Stamer
TAGS: fluid flow, homeostasis, intraocular pressure, perfusion, perturbations, shear stress
Invest. Ophthalmol. Vis. Sci.. 2024; 65(6):4. https://doi.org/10.1167/iovs.65.6.4

Includes: Supplemental Content

Glaucoma June 2024

Assessing the Efficacy of Synthetic Optic Disc Images for Detecting Glaucomatous Optic Neuropathy Using Deep Learning

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Abadh K. Chaurasia; Stuart MacGregor; Jamie E. Craig; David A. Mackey; Alex W. Hewitt
TAGS: datasets, glaucoma, optic disk, optic nerve disorders, deep learning, training
Trans. Vis. Sci. Tech.. 2024; 13(6):1. https://doi.org/10.1167/tvst.13.6.1

Includes: Supplemental Content

Glaucoma May 2024

Profiling IOP-Responsive Genes in the Trabecular Meshwork and Optic Nerve Head in a Rat Model of Controlled Elevation of Intraocular Pressure

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Diana C. Lozano; Yong-Feng Yang; William O. Cepurna; Barbara F. Smoody; Eliesa Ing; John C. Morrison; Kate E. Keller
TAGS: genes, intraocular pressure, optic disk, gene expression, trabecular meshwork, rna
Invest. Ophthalmol. Vis. Sci.. 2024; 65(5):41. https://doi.org/10.1167/iovs.65.5.41

Includes: Supplemental Content

Glaucoma May 2024

Biomechanical Correlations Between the Cornea and the Optic Nerve Head

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Manqi Pan; Sunny Kwok; Xueliang Pan; Jun Liu
TAGS: cornea, eye, optic disk, ultrasonography, intraocular pressure, donors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(5):34. https://doi.org/10.1167/iovs.65.5.34

Includes: Supplemental Content

Glaucoma May 2024

CD38 Deficiency Protects Mouse Retinal Ganglion Cells Through Activating the NAD+/Sirt1 Pathway in Ischemia-Reperfusion and Optic Nerve Crush Models

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Yulian Pang; Haijian Hu; Ke Xu; Ting Cao; Zhiruo Wang; Jiahe Nie; Haina Zheng; Hongdou Luo; Feifei Wang; Chan Xiong; Ke-Yu Deng; Hong-Bo Xin; Xu Zhang
TAGS: cd38, mice, optic nerve, reperfusion therapy, retina, physiologic reperfusion, ischemia, wounds and injuries, retinal ganglion cells
Invest. Ophthalmol. Vis. Sci.. 2024; 65(5):36. https://doi.org/10.1167/iovs.65.5.36

Glaucoma May 2024

Contrast Discrimination and Global Form Perception in Primary Open-Angle Glaucoma and Primary Angle-Closure Glaucoma

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Siddharth K. Karthikeyan; Allison M. McKendrick; Vijaya H. Pai; Neetha I. R. Kuzhuppilly; Shonraj B. Ganeshrao
TAGS: angle closure glaucoma, form perception, glaucoma, primary, open-angle glaucoma, vision, glaucoma, visual processing
Invest. Ophthalmol. Vis. Sci.. 2024; 65(5):33. https://doi.org/10.1167/iovs.65.5.33

Includes: Supplemental Content

Glaucoma May 2024

VEGF-C and 5-Fluorouracil Improve Bleb Survival in a Rabbit Glaucoma Surgery Trabeculectomy Model

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Jingyi Wu; Longfang Zhou; Yameng Liu; Xiaowei Zhang; Yuanhang Yang; Xinyuan Zhu; Qianwen Bu; Xinmiao Shan; Jia Yin; Robert N. Weinreb; Qingjun Zhou; Xiaojing Pan; Alex S. Huang
TAGS: blister, fluorouracil, oryctolagus cuniculus, surgical procedures, operative, trabeculectomy, vascular endothelial growth factor c, glaucoma, glaucoma surgery
Invest. Ophthalmol. Vis. Sci.. 2024; 65(5):32. https://doi.org/10.1167/iovs.65.5.32

Glaucoma May 2024

Retinal Nerve Fiber Layer Damage Assessment in Glaucomatous Eyes Using Retinal Retardance Measured by Polarization-Sensitive Optical Coherence Tomography

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Reshma Radhakrishnan Parakkel; Damon Wong; Chi Li; Jocelyn Cheong; Monisha Esther Nongpiur; Rachel Shujuan Chong; Tin Aung; Leopold Schmetterer; Xinyu Liu; Jacqueline Chua
TAGS: eye, glaucoma, retinal nerve fiber layer, optical coherence tomography, spectral domain-optical coherence tomography
Trans. Vis. Sci. Tech.. 2024; 13(5):9. https://doi.org/10.1167/tvst.13.5.9

Pediatric Ophthalmology & Strabismus May 2024

Measuring Visual Fields in Children With Glaucoma Using a Portable Tablet

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Viney Gupta; George X. Y. Kong; Abhishek Singh; Arnav Panigrahi; Shikha Gupta; Selwyn Prea; Algis J. Vingrys
TAGS: child, glaucoma, perimetry, tablet dosage form, visual fields, pediatrics
Trans. Vis. Sci. Tech.. 2024; 13(5):10. https://doi.org/10.1167/tvst.13.5.10

Includes: Supplemental Content

Glaucoma May 2024

TGFβ Signaling Dysregulation May Contribute to COL4A1-Related Glaucomatous Optic Nerve Damage

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Mao Mao; Yien-Ming Kuo; Alfred K. Yu; Cassandre Labelle-Dumais; Yvonne Ou; Douglas B. Gould
TAGS: glaucoma, mice, optic nerve, signal transduction, transforming growth factor-beta type ii receptor, heterozygote, eye, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2024; 65(5):15. https://doi.org/10.1167/iovs.65.5.15

Includes: Supplemental Content

Glaucoma May 2024

Intraocular Pressure While Using Gonioscopy, SLT, and Laser Iridotomy Lenses: An Ex Vivo Study

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Ticiana De Francesco; Eric Mikula; Wes Lummis; Nathan Sangalang; Iqbal Ike K. Ahmed
TAGS: eye, gonioscopy, intraocular pressure, laser iridotomy, lens (device), lens, crystalline
Invest. Ophthalmol. Vis. Sci.. 2024; 65(5):13. https://doi.org/10.1167/iovs.65.5.13

Glaucoma May 2024

Noninvasive Light Flicker Stimulation Promotes Optic Nerve Regeneration by Activating Microglia and Enhancing Neural Plasticity in Zebrafish

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Haijian Hu; Yulian Pang; Hongdou Luo; Bin Tong; Feifei Wang; Yuning Song; Qian Ying; Ke Xu; Chan Xiong; Zhida Peng; Hong Xu; Xu Zhang
TAGS: microglia, neuronal plasticity, optic nerve injuries, optic nerve regeneration, photopsia, zebrafish, retina, vision
Invest. Ophthalmol. Vis. Sci.. 2024; 65(5):3. https://doi.org/10.1167/iovs.65.5.3

Includes: Supplemental Content

Glaucoma May 2024

The Robust Lamina Cribrosa Vasculature: Perfusion and Oxygenation Under Elevated Intraocular Pressure

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Yuankai Lu; Yi Hua; Bingrui Wang; Fuqiang Zhong; Andrew Theophanous; Shaharoz Tahir; Po-Yi Lee; Ian A. Sigal
TAGS: alveolar ventilation function, cell respiration, compression, perfusion, raised intraocular pressure, vasculature, hemodynamics, vascular flow, optic disk, oxygen
Invest. Ophthalmol. Vis. Sci.. 2024; 65(5):1. https://doi.org/10.1167/iovs.65.5.1

Glaucoma April 2024

Lamina Cribrosa Insertions Into the Sclera Are Sparser, Narrower, and More Slanted in the Anterior Lamina

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Fengting Ji; Mohammad R. Islam; Bingrui Wang; Yi Hua; Ian A. Sigal
TAGS: cercopithecidae, cribriform plate, eye, sclera
Invest. Ophthalmol. Vis. Sci.. 2024; 65(4):35. https://doi.org/10.1167/iovs.65.4.35

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Protective Effect of Nicotinamide Riboside on Glucocorticoid-Induced Glaucoma: Mitigating Mitochondrial Damage and Extracellular Matrix Deposition

A Practical Framework for the Integration of Structural Data Into Perimetric Examinations

Predicting Glaucoma Surgical Outcomes Using Neural Networks and Machine Learning on Electronic Health Records

Repeatability of a Virtual Reality Headset Perimeter in Glaucoma and Ocular Hypertensive Patients

Visual Field Prognosis From Macula and Circumpapillary Spectral Domain Optical Coherence Tomography

Applicability of Oculomics for Individual Risk Prediction: Repeatability and Robustness of Retinal Fractal Dimension Using DART and AutoMorph

The Factors Affecting the Stability of IOP Homeostasis

Assessing the Efficacy of Synthetic Optic Disc Images for Detecting Glaucomatous Optic Neuropathy Using Deep Learning

Profiling IOP-Responsive Genes in the Trabecular Meshwork and Optic Nerve Head in a Rat Model of Controlled Elevation of Intraocular Pressure

Biomechanical Correlations Between the Cornea and the Optic Nerve Head

CD38 Deficiency Protects Mouse Retinal Ganglion Cells Through Activating the NAD+/Sirt1 Pathway in Ischemia-Reperfusion and Optic Nerve Crush Models

Contrast Discrimination and Global Form Perception in Primary Open-Angle Glaucoma and Primary Angle-Closure Glaucoma

VEGF-C and 5-Fluorouracil Improve Bleb Survival in a Rabbit Glaucoma Surgery Trabeculectomy Model

Retinal Nerve Fiber Layer Damage Assessment in Glaucomatous Eyes Using Retinal Retardance Measured by Polarization-Sensitive Optical Coherence Tomography

Measuring Visual Fields in Children With Glaucoma Using a Portable Tablet

TGFβ Signaling Dysregulation May Contribute to COL4A1-Related Glaucomatous Optic Nerve Damage

Intraocular Pressure While Using Gonioscopy, SLT, and Laser Iridotomy Lenses: An Ex Vivo Study

Noninvasive Light Flicker Stimulation Promotes Optic Nerve Regeneration by Activating Microglia and Enhancing Neural Plasticity in Zebrafish

The Robust Lamina Cribrosa Vasculature: Perfusion and Oxygenation Under Elevated Intraocular Pressure

Lamina Cribrosa Insertions Into the Sclera Are Sparser, Narrower, and More Slanted in the Anterior Lamina

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