Pharmacology

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Clinical Trials June 2022

Topical Ocular Anti-TNFα Agent Licaminlimab in the Treatment of Acute Anterior Uveitis: A Randomized Phase II Pilot Study

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Theodore A. Pasquali; Melissa M. Toyos; David B. Abrams; David K. Scales; John W. Seaman, III; Georges Weissgerber
TAGS: dexamethasone, pilot projects, uveitis, anterior, uveitis, safety
Trans. Vis. Sci. Tech.. 2022; 11(6):14. doi: https://doi.org/10.1167/tvst.11.6.14

Immunology and Microbiology June 2022

PPAR-α Agonist Fenofibrate Ameliorates Sjögren Syndrome–Like Dacryoadenitis by Modulating Th1/Th17 and Treg Cell Responses in NOD Mice

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Xingyi Guo; Weiyu Dang; Na Li; Ying Wang; Deming Sun; Hong Nian; Ruihua Wei
TAGS: dacryoadenitis, dry eye syndromes, fenofibrate, peroxisome proliferator-activated receptors, regulatory t-lymphocytes, mice, inbred nod, sjogren's syndrome, agonists
Invest. Ophthalmol. Vis. Sci.. 2022; 63(6):12. doi: https://doi.org/10.1167/iovs.63.6.12

Includes: Supplemental Content

Article June 2022

Serial dependence tracks objects and scenes in parallel and independently

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Thérèse Collins
TAGS: perception, shape
Journal of Vision. 2022; 22(7):4. doi: https://doi.org/10.1167/jov.22.7.4

Articles June 2022

Microvolume Analysis of Aflibercept in Aqueous Humor Using Mass Spectrometry

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Natsuka Kimura; Hidenori Takahashi; Shinichi Sakamoto; Yasuo Yanagi; Nozomi Maeshima; Ayaka Minamimoto; Noriko Iwamoto; Takashi Shimada; Ryozo Nagai; Kenichi Aizawa
TAGS: aflibercept, peptides, aqueous humor, mass spectrometry
Trans. Vis. Sci. Tech.. 2022; 11(6):7. doi: https://doi.org/10.1167/tvst.11.6.7

Includes: Supplemental Content

Articles May 2022

Antimicrobial Activity of a Triple Antibiotic Combination Toward Ocular Pseudomonas aeruginosa Clinical Isolates

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Jia A. Mei; William Johnson; Bailey Kinn; Emily Laskey; Lydia Nolin; Pratham Bhamare; Charlotte Stalker; Paul M. Dunman; Rachel A. F. Wozniak
TAGS: antibiotics, antimicrobial activity, combined antibiotics, eye, pseudomonas aeruginosa, rifampin, antibiotic resistance, bacterial, keratitis
Trans. Vis. Sci. Tech.. 2022; 11(5):26. doi: https://doi.org/10.1167/tvst.11.5.26

Includes: Supplemental Content

Clinical and Epidemiologic Research May 2022

Statin Use in Relation to Intraocular Pressure, Glaucoma, and Ocular Coherence Tomography Parameters in the UK Biobank

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Jihye Kim; Marianne T. Kennedy Neary; Hugues Aschard; Mathew M. Palakkamanil; Ron Do; Janey L. Wiggs; Anthony P. Khawaja; Louis R. Pasquale; Jae H. Kang; for the International Glaucoma Genetics Consortium (IGGC), UK Biobank Eye and Vision Consortium, and Modifiable Risk Factors for Glaucoma Collaboration
TAGS: biobanks, glaucoma, intraocular pressure, statins
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):31. doi: https://doi.org/10.1167/iovs.63.5.31

Includes: Supplemental Content

Articles May 2022

Characterization and Validation of In Vitro and In Vivo Models to Investigate TNF-α-Induced Inflammation in Retinal Diseases

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Carina M. Weigelt; Nina Zippel; Holger Fuchs; Anna-Kaisa Rimpelä; Tanja Schönberger; Birgit Stierstorfer; Remko A. Bakker; Norbert H. Redemann
TAGS: golimumab, inflammation, mice, retinal diseases, tumor necrosis factors
Trans. Vis. Sci. Tech.. 2022; 11(5):18. doi: https://doi.org/10.1167/tvst.11.5.18

Includes: Supplemental Content

Articles May 2022

Delivery of Hydrophobic Drugs to the Posterior Ocular Region by Gel-in-Water Nanoemulsion

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Jannatul Fardous; Yuuta Inoue; Kozue Yoshida; Fumiyasu Ono; Akihiro Higuchi; Hiroyuki Ijima
TAGS: biocompatibility, drug delivery systems, gel, hydrophobicity, nanogels, particle size, permeability, water, sterilization, sexual, chemical surfactants
Trans. Vis. Sci. Tech.. 2022; 11(5):16. doi: https://doi.org/10.1167/tvst.11.5.16

Includes: Supplemental Content

Articles May 2022

Modeling the Effects of Disease, Drug Properties, and Material on Drug Transport From Intraocular Lenses

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Danielle P. Clasky; Louise Meunier; Laura A. Wells
TAGS: choroid, drug clearance, drug release, drug transport, eye, fluid flow, intraocular lens implant device, mass or substance concentration per volume, steady state, vascular flow
Trans. Vis. Sci. Tech.. 2022; 11(5):14. doi: https://doi.org/10.1167/tvst.11.5.14

Includes: Supplemental Content

Retinal Cell Biology April 2022

Retinal Neuroprotective Effect of Mesenchymal Stem Cells Secretome Through Modulation of Oxidative Stress, Autophagy, and Programmed Cell Death

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Ricardo Usategui-Martín; Kevin Puertas-Neyra; Nadia Galindo-Cabello; Leticia A. Hernández-Rodríguez; Fernando González-Pérez; José Carlos Rodríguez-Cabello; Rogelio González-Sarmiento; José Carlos Pastor; Ivan Fernandez-Bueno
TAGS: apoptosis, autophagy, genes, necroptosis, nerve degeneration, neuroprotective effect, oxidative stress, proteins, rna, messenger, secretome
Invest. Ophthalmol. Vis. Sci.. 2022; 63(4):27. doi: https://doi.org/10.1167/iovs.63.4.27

Includes: Supplemental Content

Cornea March 2022

Isotretinoin Impairs the Secretory Function of Meibomian Gland Via the PPARγ Signaling Pathway

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Peng Zhang; Lei Tian; Jiayu Bao; Shang Li; Ao Li; Ya Wen; Jingyi Wang; Ying Jie
TAGS: isotretinoin, meibomian gland, meibomian gland dysfunction
Invest. Ophthalmol. Vis. Sci.. 2022; 63(3):29. doi: https://doi.org/10.1167/iovs.63.3.29

Editorial March 2022

Reviewers

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TAGS: christianity, reading (activity), alexia, cataract-alopecia-sclerodactyly syndrome, esters, glycogen storage disease type iv, sennosides, vacterl association with hydrocephalus, vision, aries trial
Journal of Vision. 2022; 22(4):10. doi: https://doi.org/10.1167/jov.22.4.10

Editorial March 2022

Reviewers

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TAGS: acetylcholine, achondroplasia, burns, calculi, christianity, cluster headache, esters, glycogen storage disease type iv, ilex, laparoscopic uterosacral nerve ablation
Invest. Ophthalmol. Vis. Sci.. 2022; 63(3):22. doi: https://doi.org/10.1167/iovs.63.3.22

Articles March 2022

The Effect of Topical Anesthetics on 16S Ribosomal Ribonucleic Acid Amplicon Sequencing Results in Ocular Surface Microbiome Research

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Heleen Delbeke; Ingele Casteels; Marie Joossens
TAGS: anesthetics, microbiome, ocular surfaces, ribosomal rna, topical anesthetics
Trans. Vis. Sci. Tech.. 2022; 11(3):2. doi: https://doi.org/10.1167/tvst.11.3.2

Articles March 2022

Shear-Thinning and Temperature-Dependent Viscosity Relationships of Contemporary Ocular Lubricants

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Wasim Kapadia; Ning Qin; Pei Zhao; Chau-Minh Phan; Lacey Haines; Lyndon Jones; Carolyn L. Ren
TAGS: eyedrops, ocular lubricants, temperature, viscosity
Trans. Vis. Sci. Tech.. 2022; 11(3):1. doi: https://doi.org/10.1167/tvst.11.3.1

Articles February 2022

PNP Hydrogel Prevents Formation of Symblephara in Mice After Ocular Alkali Injury

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Aditi Swarup; Abigail K. Grosskopf; Lindsay M. Stapleton; Varun R. Subramaniam; BaoXiang Li; Irving L. Weissman; Eric A. Appel; Albert Y. Wu
TAGS: alkalies, hydrogel, mice, wounds and injuries
Trans. Vis. Sci. Tech.. 2022; 11(2):31. doi: https://doi.org/10.1167/tvst.11.2.31

Articles February 2022

Bleb Analysis Using Anterior Segment Optical Coherence Tomography and Surgical Predictors of XEN Gel Stent

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Yuri Kim; Su-Ho Lim; Seungsoo Rho
TAGS: blister, gel, surgical procedures, operative, stents, optical coherence tomography
Trans. Vis. Sci. Tech.. 2022; 11(2):26. doi: https://doi.org/10.1167/tvst.11.2.26

Retina February 2022

In Vivo Capillary Structure and Blood Cell Flux in the Normal and Diabetic Mouse Eye

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Kosha Y. Dholakia; Andres Guevara-Torres; Guanping Feng; Derek Power; Jesse Schallek
TAGS: blood capillaries, diagnostic imaging, hyperglycemic agents, mice, blood cells, diabetes mellitus, blood glucose, retina
Invest. Ophthalmol. Vis. Sci.. 2022; 63(2):18. doi: https://doi.org/10.1167/iovs.63.2.18

Includes: Supplemental Content

Article February 2022

Crystal or jelly? Effect of color on the perception of translucent materials with photographs of real-world objects

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Chenxi Liao; Masataka Sawayama; Bei Xiao
TAGS: color, perception, gel, semantics, crystal structure
Journal of Vision. 2022; 22(2):6. doi: https://doi.org/10.1167/jov.22.2.6

Includes: Supplemental Content

Articles February 2022

Retinal Oxygen Delivery and Extraction in Ophthalmologically Healthy Subjects With Different Blood Pressure Status

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Konstantinos Pappelis; Nomdo M. Jansonius
TAGS: blood pressure, did not receive therapy or drug, hypotension, oxygen delivery, eye, oxygen saturation measurement
Trans. Vis. Sci. Tech.. 2022; 11(2):9. doi: https://doi.org/10.1167/tvst.11.2.9

Includes: Supplemental Content

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Topical Ocular Anti-TNFα Agent Licaminlimab in the Treatment of Acute Anterior Uveitis: A Randomized Phase II Pilot Study

PPAR-α Agonist Fenofibrate Ameliorates Sjögren Syndrome–Like Dacryoadenitis by Modulating Th1/Th17 and Treg Cell Responses in NOD Mice

Serial dependence tracks objects and scenes in parallel and independently

Microvolume Analysis of Aflibercept in Aqueous Humor Using Mass Spectrometry

Antimicrobial Activity of a Triple Antibiotic Combination Toward Ocular Pseudomonas aeruginosa Clinical Isolates

Statin Use in Relation to Intraocular Pressure, Glaucoma, and Ocular Coherence Tomography Parameters in the UK Biobank

Characterization and Validation of In Vitro and In Vivo Models to Investigate TNF-α-Induced Inflammation in Retinal Diseases

Delivery of Hydrophobic Drugs to the Posterior Ocular Region by Gel-in-Water Nanoemulsion

Modeling the Effects of Disease, Drug Properties, and Material on Drug Transport From Intraocular Lenses

Retinal Neuroprotective Effect of Mesenchymal Stem Cells Secretome Through Modulation of Oxidative Stress, Autophagy, and Programmed Cell Death

Isotretinoin Impairs the Secretory Function of Meibomian Gland Via the PPARγ Signaling Pathway

Reviewers

Reviewers

The Effect of Topical Anesthetics on 16S Ribosomal Ribonucleic Acid Amplicon Sequencing Results in Ocular Surface Microbiome Research

Shear-Thinning and Temperature-Dependent Viscosity Relationships of Contemporary Ocular Lubricants

PNP Hydrogel Prevents Formation of Symblephara in Mice After Ocular Alkali Injury

Bleb Analysis Using Anterior Segment Optical Coherence Tomography and Surgical Predictors of XEN Gel Stent

In Vivo Capillary Structure and Blood Cell Flux in the Normal and Diabetic Mouse Eye

Crystal or jelly? Effect of color on the perception of translucent materials with photographs of real-world objects

Retinal Oxygen Delivery and Extraction in Ophthalmologically Healthy Subjects With Different Blood Pressure Status

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