eye anatomy and disorders

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Retina November 2024

Automated Detection of Drusenoid Pigment Epithelial Detachments From Spectral-Domain Optical Coherence Tomography in Patients With AMD

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Souvick Mukherjee; Cameron Duic; Tharindu De Silva; Tiarnan D. L. Keenan; Alisa T. Thavikulwat; Emily Y. Chew; Catherine Cukras
TAGS: drusen, retinal pigment epithelial detachment, spectral domain-optical coherence tomography, reading (activity), eye
Trans. Vis. Sci. Tech.. 2024; 13(11):25. https://doi.org/10.1167/tvst.13.11.25

Includes: Supplemental Content

Clinical and Epidemiologic Research November 2024

Impact of Astigmatism on Axial Elongation in School-Age Children: A Five-Year Population-Based Study in Tianjin, China

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Dong Liang; Bei Du; Tsz-Wing Leung; Zhuzhu Liu; Qiang Su; Nan Jin; Ziyu Zhang; Mingguang He; Hua Yan; Ruihua Wei; Chea-Su Kee
TAGS: astigmatism, refractive errors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):45. https://doi.org/10.1167/iovs.65.13.45

Includes: Supplemental Content

Glaucoma November 2024

Metabolomic Profiling of Open-Angle Glaucoma Etiologic Endotypes: Tohoku Multi-Omics Glaucoma Study

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Akiko Hanyuda; Yoshihiko Raita; Takahiro Ninomiya; Kazuki Hashimoto; Naoko Takada; Kota Sato; Jin Inoue; Seizo Koshiba; Gen Tamiya; Akira Narita; Masato Akiyama; Kazuko Omodaka; Satoru Tsuda; Yu Yokoyama; Noriko Himori; Yasuko Yamamoto; Takazumi Taniguchi; Kazuno Negishi; Toru Nakazawa
TAGS: glaucoma, metabolomics, open-angle glaucoma, multiomics, metabolites
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):44. https://doi.org/10.1167/iovs.65.13.44

Includes: Supplemental Content

Glaucoma November 2024

The Mechanisms of Neuroprotection by Topical Rho Kinase Inhibition in Experimental Mouse Glaucoma and Optic Neuropathy

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Sarah E. Quillen; Elizabeth C. Kimball; Kelsey A. Ritter-Gordy; Liya Du; Zhuochen Yuan; Mary E. Pease; Salaheddine Madhoun; Thao D. Nguyen; Thomas V. Johnson; Harry A. Quigley; Ian F. Pitha
TAGS: astrocytes, did not receive therapy or drug, eye, glaucoma, mice, neuroprotection, optic nerve disorders, phosphotransferases, proteins, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):43. https://doi.org/10.1167/iovs.65.13.43

Includes: Supplemental Content

Retinal Cell Biology November 2024

Blind But Alive – Congenital Loss of atoh7 Disrupts the Visual System of Adult Zebrafish

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Juliane Hammer; Paul Röppenack; Sarah Yousuf; Anja Machate; Marika Fischer; Stefan Hans; Michael Brand
TAGS: adult, zebrafish, phenotype, visual system, retina
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):42. https://doi.org/10.1167/iovs.65.13.42

Includes: Supplemental Content

Lens November 2024

Quantitative and Rapid In Vivo Imaging of Human Lenticular Fluorescence

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Joshua M. Herzog; Angela Verkade; Volker Sick
TAGS: diagnostic imaging, fluorescence, lens, crystalline, lens (device)
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):41. https://doi.org/10.1167/iovs.65.13.41

Retina November 2024

Preservation of Murine Whole Eyes With Supplemented UW Cold Storage Solution: Anatomical Considerations

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Nicole A. Muench; Heather M. Schmitt; Cassandra L. Schlamp; An-Jey A. Su; Kia Washington; Robert W. Nickells
TAGS: cryopreservation, eye, mice
Trans. Vis. Sci. Tech.. 2024; 13(11):24. https://doi.org/10.1167/tvst.13.11.24

Includes: Supplemental Content

Erratum November 2024

Erratum in: How Modifications of Corneal Cross-Linking Protocols Influence Corneal Resistance to Enzymatic Digestion and Treatment Depth

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Trans. Vis. Sci. Tech.. 2024; 13(11):23. https://doi.org/10.1167/tvst.13.11.23

Cornea & External Disease November 2024

Efficacy of Terpinen-4-ol Combined With Eyelid Deep Cleaning for the Treatment of Demodex Blepharitis: A Randomized, Open-Label Trial

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Hao-Yu Wang; Dan Shen; Meng-Ying Qi; Chen Qiao; Lan Ke; Mingwu Wang; Qing-Yan Zeng
TAGS: blepharitis, eyelid, mites, ocular surfaces, eyelid margin, follow-up
Trans. Vis. Sci. Tech.. 2024; 13(11):22. https://doi.org/10.1167/tvst.13.11.22

Article November 2024

Modeling the dynamics of contextual cueing effect by reinforcement learning

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Yasuhiro Hatori; Zheng-Xiong Yuan; Chia-Huei Tseng; Ichiro Kuriki; Satoshi Shioiri
TAGS: learning, natural scenes, saccades
Journal of Vision. 2024; 24(12):11. https://doi.org/10.1167/jov.24.12.11

Biochemistry and Molecular Biology November 2024

Tapinarof, an Aryl Hydrocarbon Receptor Ligand, Mitigates Fibroblast Activation in Thyroid Eye Disease: Implications for Novel Therapy

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Charkira C. Patrick; Elisa Roztocil; Farha Husain; Steven E. Feldon; Collynn F. Woeller
TAGS: aryl hydrocarbon receptor, fibroblasts, graves' ophthalmopathy, ligands, signal transduction, tapinarof, platelet-derived growth factor, thymidylate synthase, proto-oncogene proteins c-akt
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):40. https://doi.org/10.1167/iovs.65.13.40

Includes: Supplemental Content

Retina November 2024

Three-Dimensional Choroidal Vessels Assessment in Age-Related Macular Degeneration

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Elham Sadeghi; Nicola Valsecchi; Mohammed Nasar Ibrahim; Katherine Du; Elli Davis; Sandeep Chandra Bollepalli; Kiran Kumar Vupparaboina; Jose Alain Sahel; Jay Chhablani
TAGS: age-related macular degeneration, cardiovascular imaging, cortical blindness, eye
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):39. https://doi.org/10.1167/iovs.65.13.39

Article November 2024

Rapid eye and hand responses in an interception task are differentially modulated by context-dependent predictability

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Jolande Fooken; Parsa Balalaie; Kayne Park; J. Randall Flanagan; Stephen H. Scott
TAGS: eye, reaction time
Journal of Vision. 2024; 24(12):10. https://doi.org/10.1167/jov.24.12.10

Cornea & External Disease November 2024

A New Method for Lateral Visualization of the Primary Cilia on the Surfaces of Cells Cultured on White Glass Rods

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Hidetoshi Tanioka; Hideto Deguchi; Shigeru Kinoshita; Chie Sotozono
TAGS: cilia, glass, rod photoreceptors, scirrhous adenocarcinoma, chronic exertional compartment syndrome
Trans. Vis. Sci. Tech.. 2024; 13(11):19. https://doi.org/10.1167/tvst.13.11.19

Includes: Multimedia, Supplemental Content

Retina November 2024

Optimization of HITI-Mediated Gene Insertion for Rhodopsin and Peripherin-2 in Mouse Rod Photoreceptors: Targeting Dominant Retinitis Pigmentosa

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Akishi Onishi; Yuji Tsunekawa; Michiko Mandai; Aiko Ishimaru; Yoko Ohigashi; Junki Sho; Kazushi Yasuda; Keiichiro Suzuki; Juan Carlos Izpisua Belmonte; Fumio Matsuzaki; Masayo Takahashi
TAGS: genes, genome editing, mice, retinitis pigmentosa, rhodopsin, rod photoreceptors, donors, plasmids, electroporation
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):38. https://doi.org/10.1167/iovs.65.13.38

Includes: Supplemental Content

Lens November 2024

In Utero/Childhood/ Adolescence Exposure to Tobacco Smoke and Elderly-Onset Cataract: A Large Prospective Cohort Study

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Chunran Lai; Yaxin Wang; Xiaomin Zeng; Zijing Du; Shan Wang; Zhanjie Lin; Yijun Hu; Ying Fang; Xiayin Zhang; Honghua Yu
TAGS: cataract, smoke, tobacco, adolescent, child, prospective studies, older adult
Trans. Vis. Sci. Tech.. 2024; 13(11):21. https://doi.org/10.1167/tvst.13.11.21

Includes: Supplemental Content

Low Vision Rehabilitation November 2024

Development and Psychometric Assessment of a Chinese Version of the Ultra-Low Vision Visual Functioning Questionnaire-50

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Jing Cong; Xinyuan Wu; Chunqiong Dong; Jing Wang; Chenli Feng; Gechun Wang; Yiting Wu; Gislin Dagnelie; Jinhui Dai; Yuanzhi Yuan
TAGS: chinese (other dialects), chinese people, psychometrics, questionnaires, vision, rasch model
Trans. Vis. Sci. Tech.. 2024; 13(11):20. https://doi.org/10.1167/tvst.13.11.20

Includes: Supplemental Content

Cornea & External Disease November 2024

Exploring New Links Among Keratoconus, Hormonal Factors, and Medications: Insights From a Case–Control Study Utilizing the All of Us Database

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Carol Beatty; Amy Estes; Hongyan Xu; Yutao Liu
TAGS: estrogen, keratoconus, pharmaceutical preparations, risk factors, obesity, medical history, dry eye syndromes
Trans. Vis. Sci. Tech.. 2024; 13(11):18. https://doi.org/10.1167/tvst.13.11.18

Retina November 2024

A High-Fidelity Computational Model for Predicting Blood Cell Trafficking and 3D Capillary Hemodynamics in Retinal Microvascular Networks

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Saman Ebrahimi; Phillip Bedggood; Yifu Ding; Andrew Metha; Prosenjit Bagchi
TAGS: blood capillaries, blood cells, computer simulation, fluid flow, hematocrit, hemodynamics, microcirculation, microvascular network, velocity, retail clinics
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):37. https://doi.org/10.1167/iovs.65.13.37

Includes: Multimedia, Supplemental Content

Cornea November 2024

Deletion of Fgfr2 in Ductal Basal Epithelium With Tamoxifen Induces Obstructive Meibomian Gland Dysfunction

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Xiaowei Yang; Xingwu Zhong; Haotian Lin; Andrew J.W. Huang; Lixing W. Reneker
TAGS: atrophy, epithelium, fgfr2 gene, meibomian gland dysfunction, mice, tamoxifen
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):36. https://doi.org/10.1167/iovs.65.13.36

Includes: Supplemental Content

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Automated Detection of Drusenoid Pigment Epithelial Detachments From Spectral-Domain Optical Coherence Tomography in Patients With AMD

Impact of Astigmatism on Axial Elongation in School-Age Children: A Five-Year Population-Based Study in Tianjin, China

Metabolomic Profiling of Open-Angle Glaucoma Etiologic Endotypes: Tohoku Multi-Omics Glaucoma Study

The Mechanisms of Neuroprotection by Topical Rho Kinase Inhibition in Experimental Mouse Glaucoma and Optic Neuropathy

Blind But Alive – Congenital Loss of atoh7 Disrupts the Visual System of Adult Zebrafish

Quantitative and Rapid In Vivo Imaging of Human Lenticular Fluorescence

Preservation of Murine Whole Eyes With Supplemented UW Cold Storage Solution: Anatomical Considerations

Erratum in: How Modifications of Corneal Cross-Linking Protocols Influence Corneal Resistance to Enzymatic Digestion and Treatment Depth

Efficacy of Terpinen-4-ol Combined With Eyelid Deep Cleaning for the Treatment of Demodex Blepharitis: A Randomized, Open-Label Trial

Modeling the dynamics of contextual cueing effect by reinforcement learning

Tapinarof, an Aryl Hydrocarbon Receptor Ligand, Mitigates Fibroblast Activation in Thyroid Eye Disease: Implications for Novel Therapy

Three-Dimensional Choroidal Vessels Assessment in Age-Related Macular Degeneration

Rapid eye and hand responses in an interception task are differentially modulated by context-dependent predictability

A New Method for Lateral Visualization of the Primary Cilia on the Surfaces of Cells Cultured on White Glass Rods

Optimization of HITI-Mediated Gene Insertion for Rhodopsin and Peripherin-2 in Mouse Rod Photoreceptors: Targeting Dominant Retinitis Pigmentosa

In Utero/Childhood/ Adolescence Exposure to Tobacco Smoke and Elderly-Onset Cataract: A Large Prospective Cohort Study

Development and Psychometric Assessment of a Chinese Version of the Ultra-Low Vision Visual Functioning Questionnaire-50

Exploring New Links Among Keratoconus, Hormonal Factors, and Medications: Insights From a Case–Control Study Utilizing the All of Us Database

A High-Fidelity Computational Model for Predicting Blood Cell Trafficking and 3D Capillary Hemodynamics in Retinal Microvascular Networks

Deletion of Fgfr2 in Ductal Basal Epithelium With Tamoxifen Induces Obstructive Meibomian Gland Dysfunction

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