Multidisciplinary Ophthalmic Imaging

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Retina January 2025

Comparison of a Novel Ultra-Widefield Three-Color Scanning Laser Ophthalmoscope to Other Retinal Imaging Modalities in Chorioretinal Lesion Imaging

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Ines D. Nagel; Anna Heinke; Akshay P. Agnihotri; Shaden Yassin; Lingyun Cheng; Andrew S. Camp; Nathan L. Scott; Fritz Gerald P. Kalaw; Shyamanga Borooah; Dirk-Uwe G. Bartsch; Arthur J. Mueller; Nehal Mehta; William R. Freeman
TAGS: color, diagnostic imaging, lasers, minimal cognitive impairment, ophthalmoscopes, retinal imaging
Trans. Vis. Sci. Tech.. 2025; 14(1):11. https://doi.org/10.1167/tvst.14.1.11

Retina January 2025

Characterization of the Disorganization of the Inner Retinal Layers in Diabetics Using Increased Axial Resolution Optical Coherence Tomography

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Katharina Wall; Lilith P. Arend; Leon von der Emde; Marlene Saßmannshausen; Frank G. Holz; Thomas Ach
TAGS: diabetes mellitus, diagnostic imaging, optical coherence tomography, spectral domain-optical coherence tomography
Trans. Vis. Sci. Tech.. 2025; 14(1):12. https://doi.org/10.1167/tvst.14.1.12

Retina January 2025

Systemic Sodium Iodate Injection as a Model for Expanding Geographic Atrophy

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Brandon D. Anderson; Brent A. Bell; Ying Song; Timothy T. Lee; Tan Wang; Joshua L. Dunaief
TAGS: age-related macular degeneration, nonexudative, atrophy, injections, iodates, sodium, mice, diagnostic imaging, retina
Trans. Vis. Sci. Tech.. 2025; 14(1):9. https://doi.org/10.1167/tvst.14.1.9

Includes: Supplemental Content

Glaucoma January 2025

In Vivo Quantification of Anterior and Posterior Chamber Volumes in Mice: Implications for Aqueous Humor Dynamics

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Daniel Kim; Raymond Fang; Pengpeng Zhang; Zihang Yan; Cheng Sun; Guorong Li; Christa Montgomery; Simon W. M. John; W. Daniel Stamer; Hao F. Zhang; C. Ross Ethier
TAGS: anterior chamber of eye, aqueous humor, diagnostic imaging, eye, mice, vaccine information sheets, volume, x-ray microtomography
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):18. https://doi.org/10.1167/iovs.66.1.18

Includes: Supplemental Content

Multidisciplinary Ophthalmic Imaging January 2025

Retinal OCT-Derived Texture Features as Potential Biomarkers for Early Diagnosis and Progression of Diabetic Retinopathy

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Sara Oliveira; Pedro Guimarães; Elisa Julião Campos; Rosa Fernandes; João Martins; Miguel Castelo-Branco; Pedro Serranho; Paulo Matafome; Rui Bernardes; António Francisco Ambrósio
TAGS: biological markers, diabetes mellitus, diabetes mellitus, type 1, diabetic retinopathy, early diagnosis, retina, streptozocin, proteins
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):7. https://doi.org/10.1167/iovs.66.1.7

Includes: Supplemental Content

Retina December 2024

Prognostic Relevance of Relative Ellipsoid Zone Reflectivity for Ellipsoid Zone Loss in Macular Telangiectasia Type 2

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Lukas Goerdt; Jose Luis Rodriguez Garcia; Sandrine H. Künzel; Kristina Pfau; Kristin Raming; Simone Tzaridis; Matthias Schmid; Frank G. Holz; Ben Isselmann; Leonie Weinhold; Sarah Thiele
TAGS: patient prognosis, telangiectasis, spectral domain-optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):36. https://doi.org/10.1167/iovs.65.14.36

Cornea & External Disease December 2024

In Vivo Contactless, Cellular-Resolution Imaging of the Healthy and Pathological Human Limbus With 250-kHz Point-Scanning SD-OCT

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Kostadinka Bizheva; Zohreh Hosseinaee; Kirsten Carter; Denise Hileeto; Brian G. Ballios; Luigina Sorbara; Hall F. Chew
TAGS: body tissue, diagnostic imaging, spectral domain-optical coherence tomography, eye, cicatrix
Trans. Vis. Sci. Tech.. 2024; 13(12):29. https://doi.org/10.1167/tvst.13.12.29

Retina December 2024

A Novel Grid Strategy for Correlating Focal Macular Anatomic Changes With Focal Changes in Choriocapillaris Perfusion

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Farhan E. Hiya; Yuxuan Cheng; Mengxi Shen; Jianqing Li; Alessandro Berni; Sandy Wenting Zhou; Gissel Herrera; Robert C. O'Brien; Giovanni Gregori; Ruikang K. Wang; Philip J. Rosenfeld
TAGS: chief complaint, drusen, eye, perfusion, reliability, diagnostic imaging, coronary arteriosclerosis, masks, computer assisted diagnosis, computer-aided detection systems
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):5. https://doi.org/10.1167/iovs.65.14.5

Retina December 2024

Characterization of the Retinal Circulation of the Mouse

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Fei Shang,; Jesse Schallek
TAGS: mice, retina circulation, vasculature, diagnostic imaging
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):3. https://doi.org/10.1167/iovs.65.14.3

Includes: Multimedia, Supplemental Content

Retina December 2024

The Umbra and the Penumbra: Longitudinal Effects of Geographic Atrophy in AMD on the Outer Choroid by Imaging Analysis and Histopathological Correlation

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Enrico Borrelli; Francesco Cappellani; Jose S. Pulido; Daniel Pauleikhoff; Imran A. Bhutto; D. Scott McLeod; Michele Reibaldi; Malia M. Edwards
TAGS: age-related macular degeneration, nonexudative, choroid, diagnostic imaging, eye, follow-up, histopathology tests, retinal pigment epithelium atrophy, chief complaint
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):2. https://doi.org/10.1167/iovs.65.14.2

Article November 2024

The choices hidden in photography

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Aaron Hertzmann
TAGS: photography, color, perception
Journal of Vision. 2024; 22(11):10. https://doi.org/10.1167/jov.22.11.10

Lens November 2024

Quantitative and Rapid In Vivo Imaging of Human Lenticular Fluorescence

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Joshua M. Herzog; Angela Verkade; Volker Sick
TAGS: diagnostic imaging, fluorescence, lens, crystalline, lens (device)
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):41. https://doi.org/10.1167/iovs.65.13.41

Multidisciplinary Ophthalmic Imaging November 2024

Evaluating the Impact of Retinal Vessel Segmentation Metrics on Retest Reliability in a Clinical Setting: A Comparative Analysis Using AutoMorph

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Samuel D. Giesser; Ferhat Turgut; Amr Saad; Jay R. Zoellin; Chiara Sommer; Yukun Zhou; Siegfried K. Wagner; Pearse A. Keane; Matthias Becker; Delia Cabrera DeBuc; Gábor Márk Somfai
TAGS: biological markers, image quality, reliability, retinal vessels
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):24. https://doi.org/10.1167/iovs.65.13.24

Includes: Supplemental Content

Multidisciplinary Ophthalmic Imaging November 2024

Distortion-Corrected Posterior Ocular Shape in Myopic Eyes Assessed by Ultrawide OCT Detects Deformations Associated With Vision-Threatening Changes

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Bingyao Tan; Janika N. Shah; Ryan P. McNabb; Swathi Jayaraman; Damon Wong; Jacqueline Chua; Marcus Ang; Seang Mei Saw; Jost B. Jonas; Anthony N. Kuo; Quan V. Hoang; Leopold Schmetterer
TAGS: eye, myopia, shape, vision
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):22. https://doi.org/10.1167/iovs.65.13.22

Includes: Supplemental Content

Artificial Intelligence November 2024

Developing a 10-Layer Retinal Segmentation for MacTel Using Semi-Supervised Learning

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Aayush Verma; Simone Tzaridis; Marian Blazes; Martin Friedlander; Aaron Y. Lee; Yue Wu
TAGS: deep learning, learning, datasets, eye, training
Trans. Vis. Sci. Tech.. 2024; 13(11):2. https://doi.org/10.1167/tvst.13.11.2

Includes: Supplemental Content

Glaucoma November 2024

Proposing a Methodology for Axon-Centric Analysis of IOP-Induced Mechanical Insult

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Manik Bansal; Bingrui Wang; Susannah Waxman; Fuqiang Zhong; Yi Hua; Yuankai Lu; Juan Reynaud; Brad Fortune; Ian A. Sigal
TAGS: axon, body tissue, intraocular pressure, optic disk, volume, reconstructive surgical procedures
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):1. https://doi.org/10.1167/iovs.65.13.1

Includes: Supplemental Content

Multidisciplinary Ophthalmic Imaging October 2024

A New Retest-Stable Tortuosity Metric for Retinal Vessel Analyses

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Samuel David Giesser; Ferhat Turgut; Amr Saad; Chiara Sommer; Yukun Zhou; Siegfried Karl Wagner; Pearse Andrew Keane; Matthias Becker; Delia Cabrera DeBuc; Gábor Márk Somfai
TAGS: reliability, retinal vessels
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):30. https://doi.org/10.1167/iovs.65.12.30

Retina October 2024

Artificial Intelligence–Assisted Perfusion Density as Biomarker for Screening Diabetic Nephropathy

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Xiao Xie; Wenqi Wang; Hongyan Wang; Zhiping Zhang; Xiaomeng Yuan; Yanmei Shi; Yanfeng Liu; Qingjun Zhou; Tingting Liu
TAGS: artificial intelligence, biological markers, diabetes mellitus, type 2, diabetic nephropathy, perfusion, screening, random forest, complex
Trans. Vis. Sci. Tech.. 2024; 13(10):19. https://doi.org/10.1167/tvst.13.10.19

Multidisciplinary Ophthalmic Imaging October 2024

Severity Stratification of Coronary Artery Disease Using Novel Inner Ellipse-Based Foveal Avascular Zone Biomarkers

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Natasa Jeremic; Maximilian Pawloff; Dmitrii Lachinov; Stephanie Rokitansky; Matthias Hasun; Franz Weidinger; Andreas Pollreisz; Hrvoje Bogunović; Ursula Schmidt-Erfurth
TAGS: biological markers, coronary arteriosclerosis, stratification
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):15. https://doi.org/10.1167/iovs.65.12.15

Includes: Supplemental Content

Retina October 2024

Critical Impact of Working Distance on OCT Imaging: Correction of Optical Distortion and Its Effects on Measuring Retinal Curvature

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Yong Woo Kim; Glen P. Sharpe; Julia Siber; Ralf Keßler; Jörg Fischer; Tilman Otto; Balwantray C. Chauhan
TAGS: diagnostic imaging, eye, optics
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):10. https://doi.org/10.1167/iovs.65.12.10

Includes: Multimedia, Supplemental Content

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Comparison of a Novel Ultra-Widefield Three-Color Scanning Laser Ophthalmoscope to Other Retinal Imaging Modalities in Chorioretinal Lesion Imaging

Characterization of the Disorganization of the Inner Retinal Layers in Diabetics Using Increased Axial Resolution Optical Coherence Tomography

Systemic Sodium Iodate Injection as a Model for Expanding Geographic Atrophy

In Vivo Quantification of Anterior and Posterior Chamber Volumes in Mice: Implications for Aqueous Humor Dynamics

Retinal OCT-Derived Texture Features as Potential Biomarkers for Early Diagnosis and Progression of Diabetic Retinopathy

Prognostic Relevance of Relative Ellipsoid Zone Reflectivity for Ellipsoid Zone Loss in Macular Telangiectasia Type 2

In Vivo Contactless, Cellular-Resolution Imaging of the Healthy and Pathological Human Limbus With 250-kHz Point-Scanning SD-OCT

A Novel Grid Strategy for Correlating Focal Macular Anatomic Changes With Focal Changes in Choriocapillaris Perfusion

Characterization of the Retinal Circulation of the Mouse

The Umbra and the Penumbra: Longitudinal Effects of Geographic Atrophy in AMD on the Outer Choroid by Imaging Analysis and Histopathological Correlation

The choices hidden in photography

Quantitative and Rapid In Vivo Imaging of Human Lenticular Fluorescence

Evaluating the Impact of Retinal Vessel Segmentation Metrics on Retest Reliability in a Clinical Setting: A Comparative Analysis Using AutoMorph

Distortion-Corrected Posterior Ocular Shape in Myopic Eyes Assessed by Ultrawide OCT Detects Deformations Associated With Vision-Threatening Changes

Developing a 10-Layer Retinal Segmentation for MacTel Using Semi-Supervised Learning

Proposing a Methodology for Axon-Centric Analysis of IOP-Induced Mechanical Insult

A New Retest-Stable Tortuosity Metric for Retinal Vessel Analyses

Artificial Intelligence–Assisted Perfusion Density as Biomarker for Screening Diabetic Nephropathy

Severity Stratification of Coronary Artery Disease Using Novel Inner Ellipse-Based Foveal Avascular Zone Biomarkers

Critical Impact of Working Distance on OCT Imaging: Correction of Optical Distortion and Its Effects on Measuring Retinal Curvature

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